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Archive > Volume 3 Issue 1 > 2011,3(1):64-65. DOI:10.3969/j.issn.1674-6384.2011.01.013 Prev Next

A New Alkaloid from Bombycis Feculae and Its α-Glucosidase Inhibitory Activity

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A New Alkaloid from Bombycis Feculae and Its α-Glucosidase Inhibitory Activity

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    摘要:


    Abstract:
    Objective To study the chemical constituents of Bombycis Feculae. Methods Chemical constituents were isolated by HPLC-ELSD. The structures of the isolated compounds were determined by spectral means. Results Two compounds were isolated and identified as 1-deoxynojirimycin (1) and (2R,3R,5R)-2-(hydroxymethyl) piperidine-3,5-diol, named as 1,3-dideoxygalatonojirimycin (2). Conclusion Compound 2 is a new alkaloid. The extract of Bombycis Feculae, compound 1 and compound 2 show inhibitory activities against α-glucosidase.

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    Project Supported:
    Key National Science & Technology Specific Projects (2009ZX09103-363)

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