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Archive > Volume 5 Issue 2 > 2013,5(2):121-124. DOI:10.3969/j.issn.1674-6348.2013.02.007 Prev Next

Original articles

Immunological Effects of Total Flavones from Leaves of Choerospondias axillaris on Mice

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    摘要:


    Abstract:
    Objective To investigate the effect of total flavones from the leaves of Choerospondias axillaris (TFLCA) on the immune function of normal mice and to provide the experimental basis for the reasonable application of C. axillaris. Methods The carbon clearance method, cutaneous delayed hypersensitivity reaction method, serum hemolysin method, and index of immune organs were used to study the effect of TFLCA on the immune function of mice. Results TFLCA could enhance the phagocytic function of mononuclear macrophage and the cutaneous delayed hypersensitivity reaction of mice, and increase the content of hemolysin antibody and the thymus index in mice. Conclusion TFLCA could improve the celiac macrophage activity and specific immunity of mice, and TFLCA, consisting with the total flavones of Choerospondiatis Fructus (TFCF), has the effect on the immune function of mice. So both TFLCA and TFCF have the regulatory effects on the immune function of mice.

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    Project Supported:
    Inner Mongolia Science and Technology Projects (20100825); Health-care Scientific Research Programs of Ministry of Health of Inner Mongolia (2010058)

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