Ethnopharmacology, phytochemistry and pharmacology of Benincasae Exocarpium: A review

doi:https://doi.org/10.1016/j.chmed.2022.10.001

Archive > Volume 15 Issue 1 > 2023,15(1):15-26. DOI:https://doi.org/10.1016/j.chmed.2022.10.001 Prev Next

冬瓜的民族藥理學(xué)、植物化學(xué)和藥理學(xué)研究進(jìn)展

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Ethnopharmacology, phytochemistry and pharmacology of Benincasae Exocarpium: A review

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摘要:

冬瓜(Benincasae Exocarpium, BE)是葫蘆科冬瓜(Benincasa hispida)的干燥外皮，是一種藥食同源的中藥。目前已從BE中分離到43種化合物，包括黃酮類化合物、生物堿、單寧、酚酸、可溶性纖維和碳水化合物?，F(xiàn)代藥理學(xué)研究和臨床實踐表明，BE具有利尿、降血脂、降血糖、抗氧化、抗菌等作用。本文對其民間用途、功能因子、藥理活性、專利及臨床應(yīng)用等方面進(jìn)行了綜述。此外，本文還對目前存在的問題進(jìn)行了探討，以供進(jìn)一步研究。本文總結(jié)的信息為藥物和食物資源的綜合利用提供了有價值的線索，并為BE藥用植物的開發(fā)提供了科學(xué)依據(jù)。

Abstract:

Benincasae Exocarpium (BE, Dongguapi in Chinese), as the dried outer pericarp of Benincasa hispida (wax gourd) in Cucurbitaceae family, is one of traditional Chinese medicines with the same origin as medicine and food. Up to now, 43 compounds were isolated from BE, including flavonoids, alkaloids, tannins, phenolic acids, soluble fiber and carbohydrates. Modern pharmacological studies and clinical practice showed that BE has diuretic, hypolipidemic effects, hypoglycemic, antioxidant, antibacterial, and other effects. The folk uses, functional factors, pharmacological activities, patents and clinical applications of BE were reviewed in this paper. In addition, the paper also discussed the current problems for the further studies. The information summarized in this paper provides valuable clues for the comprehensive utilization of medicine and food resources and gives a scientific basis for the development of medicinal plants of BE.

關(guān)鍵詞:

冬瓜;藥食同源;現(xiàn)代藥理學(xué);功能性成分

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The work was supported by the National Natural Science Foundation of China (No. 81673693) and Tianjin Intelligent Manufacturing Special Project of China (No. 20201178) for financial support.

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