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Archive > Volume 15 Issue 3 > 2023,15(3):376-382. DOI:https://doi.org/10.1016/j.chmed.2023.01.005 Prev Next

靈芝種質(zhì)資源及次生代謝調(diào)控研究進(jìn)展

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Germplasm resources and secondary metabolism regulation in Reishi mushroom (Ganoderma lucidum)

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    摘要:
    靈芝是一種具有藥用價值的大型真菌，它的次級代謝物種類復(fù)雜，三萜類化合物是其主要成分。本文首先從本草考證，種類及分布和分子水平的種類鑒定三方面介紹靈芝屬的種質(zhì)資源；其次，概述了靈芝的主要成分；最后，總結(jié)了靈芝酸的生物活性和生物合成途徑。旨在為靈芝種質(zhì)資源開發(fā)利用和靈芝酸的生物合成提供科學(xué)參考。

    Abstract:
    Ganoderma lucidum is a valuable medical macrofungus with a myriad of diverse secondary metabolites, in which triterpenoids are the major constituents. This paper introduced the germplasm resources of genus Ganoderma from textual research, its distribution and identification at the molecular level. Also we overviewed G. lucidum in the components, the biological activities and biosynthetic pathways of ganoderic acid, aiming to provide scientific evidence for the development and utilization of G. lucidum germplasm resources and the biosynthesis of ganoderic acid.

    關(guān)鍵詞:
    化學(xué)成分;靈芝;靈芝酸;種質(zhì)資源;藥理活性;次級代謝調(diào)控

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    Project Supported:
    This work was supported by the Key Scientific and Technological Grant of Zhejiang for Breeding New Agricultural Varieties (No. 2021C02074 and 2021C02073), Zhejiang Provincial Natural Science Foundation of China (No. LR21H280002) and Zhejiang Key Agricultural Enterprise Institute (No. 2017Y20001).

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