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Archive > Volume 16 Issue 3 > 2024,16(3):344-357. DOI:https://doi.org/10.1016/j.chmed.2023.04.001 Prev Next

海馬的化學(xué)成分、藥理活性和質(zhì)量評價方法：一個全面的回顧

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Chemical constituents, pharmacological activities and quality evaluation methods of genus Hippocampus: A comprehensive review

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    摘要:
    海馬是一種多基原物種，具有很高的藥用和保健價值。約有57種海馬分布于世界各地，其中約有14種可入藥，具有抗氧化、抗炎、抗抑郁、抗高血壓、抗前列腺增生、抗病毒、抗凋亡、抗疲勞等功效。這些藥理作用主要與海馬中的活性成分有關(guān)，包括氨基酸、豐富的蛋白質(zhì)（肽和寡肽）、脂肪酸、核苷類、甾體類等小分子化合物。海馬物種的鑒定手段主要有形態(tài)學(xué)鑒別、顯微鑒別、薄層色譜法、指紋圖譜法和基因組學(xué)法等。本綜述將為今后海馬的探索、進一步研究和精確用藥提供一定啟示。

    Abstract:
    The genus Hippocampus is a multi-origin animal species with high medicinal and healthcare values. About 57 species of Hippocampus spread worldwide, of which about 14 species can be used as medicine, showing anti-oxidation, anti-inflammation, anti-depressant, anti-hypertension, anti-prostatic hyperplasia, antivirus, anti-apoptotic, antifatigue, and so on. And those pharmacological effects are mainly related to their active ingredients, including amino acids, abundant proteins (peptides and oligopeptides), fatty acids, nucleosides, steroids, and other small molecular compounds. The main means of authentication of Hippocampus species are morphological identification, microscopic identification, thin layer chromatography method, fingerprint method and genomics method. This review will provide useful insight for exploration, further study and precise medication of Hippocampus in the future.

    關(guān)鍵詞:
    化學(xué)成分;海馬屬;藥理活性;質(zhì)量評估

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    Project Supported:
    We are extremely grateful for the financial support of the National key research and development program 2019YFC1711505, Hebei Industrial Innovation and Entrepreneurship Team (No. 215A2501D), Key Research and Development Projects in Hebei Province (No. 21372503D), Wuhan Science and Technology Project (No. 2020020602012116).

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