摘 要：目的 建立 HPLC 法測定荔枝核方中丹參素。方法 SinoChrom ODS-BP 色譜柱（200 mm×4.6 mm，5 μm），流動相為甲醇–1% 醋酸溶液（5∶95），柱溫為室溫，體積流量1.0 mL/min，檢測波長280 nm。結(jié)果 丹參素在9.54～95.4 μg/mL 線性關(guān)系良好，r＝0.999 6；平均回收率為100.2%（RSD＝1.8%，n＝9）。結(jié)論 該方法操作簡便，其他組分對測定無干擾，準(zhǔn)確性和重現(xiàn)性好，可作為荔枝核方的質(zhì)量控制方法。

Abstract: Objective To establish a method for determining the content of propanoid acid by HPLC．Methods The HPLC performed on a SinoChrom ODS-BP column（200 mm×4.6 mm，5 μm），mobile phase consisted of methanol-1% acetic acid（5∶95），column temperature was room temperature，flow rate was 1.0 mL/min，detection wavelength was 280 nm．Results The calibration curve was linear in the range of 9.54—95.4 μg/mL with good linearity（r＝0.999 6）．The average recovery was 100.2%（RSD＝1.8%，n＝9）．Conclusion The method is convenient，reliable，accurate and repeatable，and can be used in quality control of Semen Litchi Compound．