[關(guān)鍵詞]
[摘要]
脂肪乳作為一種給藥載體，不論處方組成還是制備工藝已經(jīng)日益成熟。SolEmul技術(shù)給油水均難溶藥物的制劑帶來(lái)希望；自乳化給藥系統(tǒng)可提高難溶性藥物的生物利用度；陽(yáng)離子脂肪乳不僅延長(zhǎng)藥物體內(nèi)循環(huán)時(shí)間，還使肺部給藥技術(shù)得到長(zhǎng)足發(fā)展；同時(shí)脂肪乳在細(xì)胞靶向和中藥制劑的研究中也呈現(xiàn)出獨(dú)特的優(yōu)勢(shì)。隨著載藥脂肪乳各項(xiàng)研究的深入和發(fā)展，未來(lái)應(yīng)用范圍必將更加廣泛。
[Key word]
[Abstract]
As a drug carrier, lipid emulsion has become increasingly mature regardless the prescription composition or preparation methods. SolEmul technology brings hope to insoluble drugs in oil and water; self-emulsifying drug delivery system can improve the bioavailability of the insoluble drugs; cationic lipid emulsion not only extends the drug circulation time, but also greatly develops the pulmonary drug delivery technology; while lipid emulsion has also shown a distinct advantage in cell targeting studies and Chinese medicine formulations. As the drug-loaded lipid emulsion is in-depth study and development, the future will be having more wide range of applications.
[中圖分類號(hào)]
[基金項(xiàng)目]
國(guó)家重點(diǎn)基礎(chǔ)研究發(fā)展計(jì)劃項(xiàng)目（2010CB735602）；天津市科技支撐項(xiàng)目（09ZCKFSH01200）
