目的 建立復(fù)方洋參歸地丸的質(zhì)量標(biāo)準(zhǔn)。方法 采用薄層色譜法對(duì)制劑中當(dāng)歸、川芎、何首烏、石菖蒲、黃芪進(jìn)行定性鑒別；采用高效液相色譜–蒸發(fā)光散射（HPLC-ELSD）法測(cè)定人參皂苷Rb1。結(jié)果 薄層色譜鑒別的色譜斑點(diǎn)清晰，陰性對(duì)照無(wú)干擾。人參皂苷Rb1在1.832～18.320 μg呈良好的線性關(guān)系，平均回收率為100.06%，RSD為1.69%（n=6）。結(jié)論 所建立的方法簡(jiǎn)便可行，專屬性強(qiáng)，重現(xiàn)性好，可用于復(fù)方洋參歸地丸的質(zhì)量控制。

Objective To establish the quality control methods for Compound Yangshen Guidi Pills. Methods The method of TLC was used to qualitatively identify Angelicae Sinensis Radix, Chuanxiong Rhizoma, Polygoni Multiflori Radix , Acori Tatarinowii Rhizoma, and Astragali Radix. The content of ginsenoside Rb1 was determined by HPLC-ELSD. Results All herbal drugs in Compound Yangshen Guidi Pills were well identified by TLC and the spots were clear and without interference. The linear range of ginsenoside Rb1 was 1.832—18.320 μg, with the average recovery of 100.06%, and the RSD of 1.69% (n=6). Conclusion The established method is simple, feasible, and can be used for the quality control of Compound Yangshen Guidi Pills.