目的 對豨桐滴丸和膠囊進行溶出度的比較。方法 采用HPLC法測定樣品中奇壬醇，并以此為指標比較了豨桐滴丸和膠囊在水、0.1 mol/L HCl、0.5%十二烷基硫酸鈉中的溶出度。結(jié)果 在30 min時，豨桐滴丸在3種不同介質(zhì)的溶出度達到81.24%、80.24%、88.72%，而豨桐膠囊只有71.35%、70.35%、76.95%。結(jié)論 豨桐滴丸中奇壬醇的溶出明顯優(yōu)于豨桐膠囊。

Objective To compare the dissolution of Xitong Dropping Pills and Xitong Capsule. Methods Contents of kirenol in Xitong Dropping Pills and Xitong Capsule were determined by HPLC, and the dissolutions in three different dissolution media water, 0.1 mol/L HCl, and 0.5% sodium dodecyl sulfate (SDS) were compared. Results The dissolutions of kirenol in Xitong Dropping Pills in three different dissolution media were 81.24%, 80.24%, and 88.72% in 30 min, while the dissolutions of Xitong Capsule were 71.35%, 70.35%, and 76.95%, respectively. Conclusion The dissolution of kirenol in Xitong Dropping Pills is higher than that in Xitong Capsule