[關(guān)鍵詞]
[摘要]
薏苡仁油及其有效成分薏苡仁酯具有直接的抗頭頸部癌作用,也可通過提高機體的免疫功能間接殺傷癌細胞。其與放療或化療藥聯(lián)用,不僅可以對抗放、化療抑制免疫功能等不良反應(yīng),提高患者的生存質(zhì)量,甚至可以提高癌灶緩解率,減少腫瘤復(fù)發(fā),延長生命,具有開發(fā)成抗頭頸部癌新藥的潛力。綜述薏苡仁油抗頭頸部癌的藥理作用、作用機制及臨床應(yīng)用的研究進展。
[Key word]
[Abstract]
Coicis Semen oil and its active constituent coixenolide not only have the directly effect on kill cephalocervical cancer, but also have the indirect anti-cancer action by enhancement of immune function. In combination with chemotherapy or radiotherapy, it could reduce the adverse reactions of chemotherapy or radiotherapy, such as inhibition of immune function, increase living quality, enhance remission rate of cancer focus, decrease tumorous recurrence, and prolong life. Therefore, it has great potential for development into new drug against cephalocervical cancer. The research advances in the pharmacological effects, mechanism, and clinical application of Coicis Semen oil against cephalocervical cancer are reviewed in this paper.
[中圖分類號]
[基金項目]