蒿屬植物在世界各國胃腸道疾病傳統(tǒng)防治中有廣泛應(yīng)用，現(xiàn)代藥理研究驗(yàn)證了蒿屬植物提取物及其活性成分異澤蘭黃素、dehydryleucodine等的臨床前及臨床治療效果。艾蒿、茵陳等蒿屬植物是傳統(tǒng)中藥，具有廣泛的藥理活性；然而，國內(nèi)對其在胃腸道疾病防治中的應(yīng)用及現(xiàn)代研究相對滯后。主要綜述了蒿屬植物在胃腸道疾病防治中的藥理作用及其機(jī)制研究進(jìn)展，以期為蒿屬植物的創(chuàng)新應(yīng)用及中藥現(xiàn)代化研究提供借鑒。

Artemisia L. species were used in gastrointestinal protection widely around the world. Modern researches showed that Artemisia L. plant extracts and their active constituents, eupatilin and dehydryleucodine, showed positive effects against gastrointestinal diseases in preclinical and clinical trials. Plants in Artemisia L., such as A. verlotorum and A. scoparia, are widely used in traditional Chinese medicines (TCM) with a wide range of pharmacological activities. However, their application in prevention and treatment of gastrointestinal diseases and their modern researches have lagged behind in our country. This article reviews the pharmacologic effect and the mechanism of the plants in Artemisia L. for gastrointestinal protection, which could provide the reference for innovative application and modernization of TCM.