[關鍵詞]
[摘要]
目的 研究四君補鐵生血顆粒治療脾氣虛型缺鐵性貧血的臨床療效。方法 將60例脾氣虛型缺鐵性貧血患者隨機分為兩組,治療組30例,對照組30例。治療組飯后口服四君補鐵生血顆粒1包/次,3次/d,對照組飯后口服枸櫞酸鐵片2片/次,3次/d,兩組療程均為3個月,隨訪3個月。觀察治療前后血紅蛋白量、紅細胞數(shù)、血清鐵蛋白、中醫(yī)癥狀評分變化,同時觀察不良反應的情況。結果 治療后兩組血紅蛋白、紅細胞均明顯高于治療前,中醫(yī)征候評分明顯降低;臨床癥狀改善,血紅蛋白量、紅細胞數(shù)、血清鐵蛋白升高,治療組明顯優(yōu)于對照組;治療組的不良反應明顯低于對照組。結論 四君補鐵生血顆粒治療脾氣虛型缺鐵性貧血在改善臨床癥狀、促進鐵吸收、升高血紅蛋白和紅細胞方面優(yōu)于枸櫞酸鐵片,且不良反應明顯少于枸櫞酸鐵片,值得臨床進一步研究。
[Key word]
[Abstract]
Objective To study the clinical efficacy of Sijun Butie Shengxue Granules (SBSG,used for supplement of iorn) on the treatment of iron deficiency anemia (IDA) induced by spleen-Qi deficiency (SQD). Methods A total of 60 patients with IDA induced by SQD were randomly divided into treatment (30) and control (30) groups. The patients in the treatment group were po administered with SBSG, a packet once after a meal, three times daily; The patients in the control group were po administered with ferric citrate tablets, two tablets once after a meal, three times daily; Both of the two groups were consecutively adminstered for three months; And the patients were followed up for three months. The amount of hemoglobin, red blood cell count, serum ferritin, and the symptom score change of traditional Chinese medicines (TCM) were observed before and after the treatments and the adverse reactions of SBSG were observed as well. Results After the treatment, the amount of hemoglobin and red blood cell acount were significantly increased, and the symptom score change of TCM was significantly decreased. The clinical symptoms were improved, the amount of hemoglobin, red blood cell count, and serum ferritin in the treatment group were significantly increased, and the adverse reactions in the treatment group were significantly lessened compared with the control group. Conclusion SBSG could significantly improve the clinical symptoms of patients with IDA induced by SQD, help iron absorption, and increase hemoglobin and red blood cells in the treatment group better than ferric citrate tablets, which is worthy of further study in clinic.
[中圖分類號]
[基金項目]
陜西省中醫(yī)管理局科研招標課題(1c19)