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[摘要]
目的 研究闊葉五層龍醋酸乙酯部位的化學成分。方法 采用硅膠柱色譜、葡聚糖凝膠柱色譜、ODS C18反相硅膠柱色譜相結合的方法進行分離純化,根據(jù)化合物的理化性質和波譜數(shù)據(jù)鑒定已分得的化合物結構。結果 分離鑒定了7個化合物,分別為15-羥基-24-降甲基木栓烷-5-烯-1,3-二酮(1)、白樺脂酸(2)、2,3,11-三羥基烏蘇-12-烯(3)、3,21-二羥基齊墩果-12-烯-28-酸甲酯(4)、magellanin(5)、胡蘿卜苷(6)、D-甘油-D-半乳庚醇(7)。結論 化合物3~5、7為首次從翅子藤科分離得到,化合物1、2為首次從該植物中分離得到。
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[Abstract]
Objective To study the chemical constituents in the ethyl acetate extracting fraction from Salacia amplifolia. Methods The chemical constituents in the ethyl acetate fraction from S. amplifolia were isolated and purified by chromatography on silica gel, Sephadex LH-20, and ODS C18 reverse phase silica gel columns, and their chemical structures were identified by the physicochemical and spectroscopic data. Results Seven compounds were isolated and identified as 15-hydroxy-24-nor-friedel-5-ene-1,3-dione (1), pyracrenic acid (2), 2,3,11-trihydroxy-urs-12-ene (3), methyl-3,21-dihydroxy-olean-12-en-28-oate (4), magellanin (5), daucosterol (6), and D-glycero-D-galacto-heptitol (7). Conclusion Compounds 3—5 and 7 are isolated from the plants in Hippocrateaceae family for the first time and compounds 1 and 2 are isolated from this plant for the first time.
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