目的 探討硝苯地平控釋片聯(lián)合強力定眩片治療陰虛陽亢型1、2級原發(fā)性高血壓的臨床療效。方法 將96例陰虛陽亢型1、2級原發(fā)性高血壓患者隨機分成對照組和觀察組。對照組給予硝苯地平控釋片30 mg，1次/d；觀察組給予硝苯地平控釋片30 mg，1次/d，強力定眩片6片，3次/d，兩組均治療12周。治療結(jié)束后，測量患者的血壓，計算血壓療效以及中醫(yī)證候療效。結(jié)果 兩組治療后收縮壓、舒張壓較治療前均明顯降低（P＜0.05），觀察組的總有效率85.4%，明顯高于對照組的64.6%（P＜0.05）；觀察組的證候療效總有效率為89.5%，明顯高于對照組的58.3%（P＜0.05）。結(jié)論 硝苯地平控釋片聯(lián)合強力定眩片治療陰虛陽亢型1、2級原發(fā)性高血壓，比單獨應(yīng)用硝苯地平控釋片更利于血壓達(dá)標(biāo)，可更好地控制臨床癥狀。

Objective To explore the effect of Nifedipine Controlled-release Tablets combined with Qiangli Dingxuan Tablets on the grades 1 and 2 primary hypertension with the syndrome of Yin deficiency and Yang hyperactivity. Methods Patients (96 cases) with grades 1 and 2 primary hypertension of Yin deficiency and Yang hyperactivity were randomly divided into control group and observation group. The patients in the control group were administered with 30 mg Nifedipine Controlled-release Tablets once daily, and the patients in the observation group were administered with 30 mg Nifedipine Controlled-release Tablets once daily and six pills of Qiangli Dingxuan Tablets three times daily. Both groups were treated for 12 weeks. At the end of the treatment, the blood pressure of patients was measured, and the curative effect of blood pressure and the symptoms curative effect would be calculated. Results After the treatment, systolic pressure and diastolic pressure were obviously descended compared with those before treatment (P < 0.05). The efficiencies of the control and observation groups was 85.4% and 64.6% with significant difference (P < 0.05). Symptoms curative effect in the observation group was 89.5%, which was also obviously higher than 58.3% in the control group (P < 0.05). Conclusion Nifedipine Controlled-release Tablets combined with Qiangli Dingxuan Tablets could control blood pressure on grades 1 and 2 primary hypertension of Yin deficiency and Yang hyperactivity, which is better than Nifedipine Controlled-release Tablets treatment alone.