目的 了解荊州市第一人民醫(yī)院門診降壓藥的用藥合理性以及用藥特點(diǎn)。方法 調(diào)查荊州市第一人民醫(yī)院2012年1月至2013年2月門診降壓藥使用處方共10 305張以及各種降壓藥的銷售量，計(jì)算各種降壓藥的用藥頻度（DDDs）、藥物利用指數(shù)（DUI）、藥物日均費(fèi)用（DDDc），并通過(guò)各藥的DDDs排序（A）和用藥金額排序（B），算出比值（B/A）。結(jié)果 各種降壓藥的使用情況基本合理，其中依那普利片（揚(yáng)子江）以及左旋氨氯地平片（浙江昂利康）的DUI值＞1；倍他樂(lè)克緩釋片的DDDc最高，為8.44；單片復(fù)方制劑（SPC）的使用率為23%。結(jié)論 荊州市第一人民醫(yī)院門診降壓藥的使用情況基本合理，醫(yī)生和患者更傾向于選擇價(jià)格合理、依從性好以及病人獲益好的降壓藥，其中SPC可能具有優(yōu)勢(shì)。

Objective To research the rationality and characteristics of the usage status of antihypertensive agents in outpatient clinic of the First People's Hospital of Jingzhou. Methods We investigated the prescriptions (10 305) about antihypertensive agents and the sales during January 2012 to February 2013 in the First People's Hospital of Jingzhou. The defined daily dose sum (DDDs), drug utilization index (DUI), defined daily dose cost (DDDc), DDDs sequence (A), cost sequence (B), and the index of synchronization (B/A) were calculated. Results The usage of antihypertensive agents was basically reasonable, and the DUI values of Enalapril Maleate Tablets (Yangzijiang) and Levamlodipine Besylate Tablets (Anglikang, Zhejiang) were more than 1. The DDDc of Betaloc Sustained-release Tablets was the highest, 8.44, and the proportion of single-pill combination (SPC) was 23%. Conclusion The usage status of antihypertensive agents in outpatient clinic of the First People's Hospital of Jingzhou is basically reasonable. Doctors and patients incline to choose the antihypertensive agents that have superiorities in price, compliance, and benefit. SPC may have superiorities.