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[摘要]
目的 研究金銀忍冬葉Lonicera macckii (Rupr.) Maxim.的化學成分。方法 采用硅膠柱色譜、Sephadex LH-2柱色譜、重結晶等方法進行分離純化,根據理化性質和波譜數據鑒定化合物的結構。結果 從金銀忍冬葉中分離鑒定了12個化合物,分別為山柰酚(1)、芹菜素(2)、金絲桃苷(3)、芹菜素-7-O-β-D-吡喃葡萄糖苷(4)、金圣草素-4′-O-β-D-葡萄糖苷(5)、木犀草素-7-O-β-D-吡喃葡萄糖苷(6)、裂環(huán)馬錢素酸(7)、獐牙菜苷(8)、3,5-O-二咖啡?;鼘幩峒柞ィ?)、齊墩果酸(10),胡蘿卜苷(11)、β-谷甾醇(12)。結論 化合物1~6、8~12為首次從該植物中分離得到,化合物5為首次從該屬植物中分離得到。
[Key word]
[Abstract]
Objective To study the chemical constituents from the leaves of Lonicera macckii. Methods The compounds were isolated and purified gel column chromatography, Sephadex LH-2 column chromatography and recrystallization, and their structures were identified by spectral analyses and physiochemical properties. Results Twelve compounds were isolated and identified as kaempferol (1), apigenin (2), hyperoside (3), apigenin-7-O-β-D-glucopyranoside (4), chrysoeri-ol-4′-O-β-D-glucopyranoside (5), luteolin-7-O-β-D-glucopyranoside (6), secologanin acid (7), sweroside (8), methyl 3,5-O-dicaffeoylquinate (9), oleanolic acid (10), β-sitosterol (11), and daucosterol (12), respectively. Conclusion Compounds 1—6 and 8—12 are isolated from this plant for the first time, and compound 5 is isolated from this genus for the first time.
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