[關(guān)鍵詞]
[摘要]
目的 觀察額力根古日古木-7治療酒精性肝病的臨床療效和安全性。方法 選取內(nèi)蒙古民族大學(xué)附屬醫(yī)院2011年5月—2013年5月收治的60例酒精性肝病患者,隨機(jī)分為治療組(30例)和對(duì)照組(30例),兩組均行嚴(yán)格戒酒,加強(qiáng)營(yíng)養(yǎng)等支持治療;對(duì)照組口服護(hù)肝片,4片/次,3次/d;治療組口服蒙藥額力根古日古木-7,5 g/次,2次/d。兩組均治療1個(gè)月。治療結(jié)束后,比較兩組患者的臨床療效和治療前后患者的癥狀積分、肝功能指標(biāo)、肝/脾CT比值變化。結(jié)果 治療后治療組患者總有效率93.33%,對(duì)照組為70.00%,兩組差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。治療前后兩組患者蒙醫(yī)癥候積分、肝功能、肝/脾CT比值均得到明顯改善,兩組差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論 額力根古日古木-7治療酒精性肝病有很好的療效,可有效恢復(fù)患者的肝功能,治療過程中的不良反應(yīng)較少,值得臨床應(yīng)用。
[Key word]
[Abstract]
Objective To observe the efficacy and safety of Eligengurigumu-7 in the treatment of alcoholic liver diseases. Methods A total of 60 patients with alcoholic liver diseases from the Affiliated Hospital of Inner Mongolia University for Nationalities during May, 2011 to May, 2013 were randomly divided into treatment (30 cases) and control (30 cases) groups. All the patients were performed strictly to stop drinking and strengthen nutrition. The patients in the control group were po administered with Hugan Tablet, once four pieces, three times daily. The patients in the treatment group were po administered with Eligengurigumu-7, once 5 g, twice daily. The patients in the two groups were treated for 1 month. The clinical efficacy, symptom score, index of liver function, and liver and spleen CT ratio were observed before and after the treatment. Results The efficiency for the patients in both the treatment and control groups were 93.33% and 70.00% with the significant difference (P < 0.05). After treatment, Mongolian medicine symptom score, liver function, and liver and spleen CT ratio of two groups were improved significantly (P < 0.05). Conclusion Eligengurigumu-7 has an accurate curative effect on alcoholic liver diseases, and can recover liver function effectively with low incidence of adverse drug reactions, which could be used in clinic.
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