毛茛科唐松草屬植物由于具有較高的藥用價(jià)值，在我國廣泛應(yīng)用。唐松草屬植物的生物堿屬于異喹啉類，包括生物堿單聚物如簡(jiǎn)單異喹啉類、芐基異喹啉類、阿樸菲類、原小檗堿類、嗎啡烷類、異帕威類等；此外還存在大量的二聚生物堿，主要類型有雙芐基異喹啉類、阿樸菲–芐基異喹啉類、原小檗堿–芐基異喹啉類、阿樸菲–原小檗堿類等；具有抗腫瘤、抗寄生蟲、抗血小板聚集、抗矽肺、抗病毒等藥理作用。主要對(duì)唐松草屬植物中生物堿類化學(xué)成分和藥理作用的研究進(jìn)展進(jìn)行綜述，為該屬植物資源的開發(fā)利用提供參考。

The plants in Thalictrum L., Ranunculaceae family are widely used in China because of their officinal values. The main active constituents from Thalictrum L. are isoquinoline alkaloids including simple isoquinolines, benzylisoquinolines, aporphins alkaloids, proberberines, morphinans, and isopavines. There are also a lot of dimeric alkaloids including dibenzylisoquinolines, aporphinoid-benzylisoquinolines, proberberine-benzylisoquinolines, and aporphinoid-proberberines. In addition, they play an important role in anti-cancer, anti-parasites, anti-platelet aggregation, anti-silicosis, and anti-virus actions. This article mainly summarizes the chemical constituents and pharmacological activities of alkaloids from plants in Thalictrum L. in recent years, and provides a reference for the development and utilization of the plants of Thalictrum L.

國家自然科學(xué)基金資助項(xiàng)目（81172958）；國家基礎(chǔ)科學(xué)人才培養(yǎng)基金項(xiàng)目（J1103606）