目前，心血管疾病、癌癥、敗血癥、腦組織損傷、糖尿病和神經(jīng)性的疾病在全球的發(fā)病率非常高，在這些疾病中細(xì)胞色素C（cytochrome C，Cyt-C）均表現(xiàn)出不同程度的代謝紊亂。許多中藥提取物、有效部位和化學(xué)成分對(duì)這些疾病有良好的治療作用和較小的副作用。中藥主要是通過影響疾病相關(guān)組織或細(xì)胞線粒體內(nèi)的Cyt-C的產(chǎn)生或釋放，調(diào)控相應(yīng)靶細(xì)胞的凋亡，進(jìn)而防治相應(yīng)的疾病。查閱近年來的相關(guān)文獻(xiàn)報(bào)道，綜述了通過調(diào)控線粒體通路Cyt-C實(shí)現(xiàn)治療疾病的中藥提取物、有效部位和化學(xué)成分，希望能提高對(duì)中藥在防病治病中作用機(jī)制的認(rèn)識(shí)。

At present, cardiovascular disease, cancer, sepsis, damage of brain tissue, diabetes and neurological diseases have high incidence worldwide, cytochrome C (Cyt-C) shows different degrees of metabolism disorders in these diseases. Many herbal extracts, effective fractions and chemical constituents have a better therapeutic effect and less side effects in treatment of these diseases. Traditional Chinese medicine regulate corresponding target cells apoptosis, and corresponding prevent and cure the diseases, mainly by influencing the produce or release of Cyt-C of diseases related tissue or cell mitochondria. According to the relevant literature in recent years, we reviewed the herbal extracts, effective fractions and chemical constituents by regulating Cyt-C for diseases treatment, hoping to a better understanding on the mechanism of traditional Chinese medicine in the disease prevention.