目的 研究苦瓜莖葉醋酸乙酯部位的化學(xué)成分，為進(jìn)一步開發(fā)利用苦瓜莖葉提供依據(jù)。方法 采用反復(fù)硅膠柱色譜、反相ODS柱色譜、Sephadex LH-20等柱色譜進(jìn)行分離純化，并根據(jù)波譜數(shù)據(jù)鑒定化合物的結(jié)構(gòu)。結(jié)果 分離得到3種苦瓜三萜，分別鑒定為苦瓜素I（1）、kuguacin N（2）、3,7-二羥基-23(R)-乙氧基-19-醛基-5,24-二烯醇（3）。結(jié)論 化合物3為新化合物，命名為23-乙基苦瓜素I。

Objective To investigate the chemical constituents in ethyl acetate fraction from the fresh vines and leaves of Momordica charantia, so as to provide a basis for the further development and utilization. Methods Chemical constituents were isolated and purified by chromatography on silica gel and octadecylsilanized (ODS) silica gel columns, and the structures were identified on the basis of spectroscopic data. Results Three cucurbitane triterpenoids were isolated and they were identified as momordicine I (1), kuguacin N (2), and 3,7-dihydroxycucurbita-23(R)-ethoxy-5,24-dien-19-al (3). Conclusion Compound 3 is a new compound named 23-ethyl momordicine I.