[關鍵詞]
[摘要]
目的 觀察沙美特羅替卡松粉吸入劑聯(lián)合清肺消炎丸治療支氣管哮喘急性發(fā)作的臨床療效。方法 選取2012年6月-2013年6月天津市第三醫(yī)院收治的60例哮喘急性發(fā)作期輕、中度患者,分為對照組和治療組,每組各30例。兩組患者均按需使用速效β受體激動劑萬托林。對照組給予沙美特羅替卡松粉吸入劑,1吸/次,2次/d。治療組在對照組的基礎上給予清肺消炎丸,8 g/次,3次/d。兩組療程均為14 d。觀察兩組患者治療前后的臨床療效,肺通氣功能及癥狀、體征的持續(xù)時間。結果 治療后,治療組有效率明顯高于對照組,差異具有統(tǒng)計學意義(P<0.05);兩組患者治療后肺通氣功能均優(yōu)于治療前,且治療組比對照組肺通氣功能改善更明顯,差異具有統(tǒng)計學意義(P<0.05);治療組的胸悶、氣短消失時間,咳嗽緩解時間及哮鳴音消失時間明顯短于對照組,兩組比較差異有統(tǒng)計學意義(P<0.05)。結論 沙美特羅替卡松粉吸入劑聯(lián)合清肺消炎丸治療支氣管哮喘急性發(fā)作療效顯著,值得臨床推廣。
[Key word]
[Abstract]
Objective To observe the clinical efficacy of Salmeterol and Fluticasone Propionate Powder for Inhalation combined with Qingfei Xiaoyan Pills in the treatment of acute attack of bronchial asthma. Methods Patients (60 cases) with acute attack of bronchial asthma in Tianjin Third Hospital from June 2012 to June 2013 were randomly divided into treatment and control groups (30 cases in each group). The patients in the two groups were given short-acting β-agonists Ventolin according to the need. The patients in the control group were given Salmeterol and Fluticasone Propionate Powder for Inhalation, one sucktion once, two times daily. The patients in the treatment group were given Qingfei Xiaoyan Pills on the basis of the control group, 8 g once, three times daily. The patients in the both groups were treated for 14 d. The clinical efficacy, pulmonary function, and the duration of symptoms and signs were compared for the patients between the two groups. Results After the treatment, the effective rates in the treatment group were higher than those in the control group with significant difference (P < 0.05). The pulmonary function of the patients after the treatment was significantly improved. The lung function index was significantly higher than that of the patients in the control group, and there was a significant difference between the two groups (P< 0.05). The disappear time of chest tightness, the ease time of cough, and the disappear time of wheezing sound were shorter than those of the patients in the control group with significant difference (P < 0.05).Conclusion Salmeterol and Fluticasone Propionate Powder for Inhalation combined with Qingfei Xiaoyan Pills has the remarkable clinical efficacy in the treatment of acute attack of bronchial asthma. It is worthy of clinical application.
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