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[摘要]
目的 探討小兒復(fù)方四維亞鐵散對(duì)小兒厭食癥的治療效果及其對(duì)患兒血清淀粉酶(AMS)、胃泌素(Gas)水平的影響。方法 選取2012年1月-2013年12月在遂寧市中心醫(yī)院門診就診的84例厭食癥患兒為研究對(duì)象,根據(jù)隨機(jī)數(shù)字表將患兒分為對(duì)照組和治療組,每組各42例。對(duì)照組患兒口服葡萄糖酸鋅口服液,6個(gè)月~1歲2.5 mL/次,1~3歲5 mL/次,3~5歲10 mL/次,5~8歲15 mL/次,3次/d。治療組口服小兒復(fù)方四維亞鐵散,<1歲0.5包/次,1~3歲1包/次,4~6歲1.5包/次,7~12歲2包/次,1~2次/d。兩組患者2周為1個(gè)療程,均持續(xù)服用2個(gè)療程。治療后,觀察兩組患兒的療效,并比較兩組治療前后體質(zhì)量、體質(zhì)量身高指數(shù)(BMI)、血紅蛋白(Hb)、血清Zn、AMS、Gas水平的變化。結(jié)果 治療組和對(duì)照組的總有效率分別為95.24%、76.19%,兩組比較差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。治療后,兩組患兒體質(zhì)量、BMI、Hb、Zn、AMS、Gas水平均高于治療前,且治療組顯著高于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論 小兒復(fù)方四維亞鐵散對(duì)小兒厭食癥有較好的臨床療效,能有效增加患兒體質(zhì)量和BMI,改善患兒貧血癥狀,值得臨床推廣應(yīng)用。
[Key word]
[Abstract]
Objective To investigate the effect of Pediatric Compound Four Vitamins and Ferrous Fumarate Powder in the treatment of infantile and children's anorexia and its effects on serum amylase (AMS) and gastrin (Gas) levels. Methods Children with anorexia (84 cases) who came to Center Hospital of Suining City from January 2012 to December 2013 were chosen for the study. They were divided into control and treatment groups based on a random number table, and there were 42 cases in each group. The patients in the control group were po administered with Zinc Gluconate Oral Solution, 6 months to 1-year old children by 2.5 mL/time, 1-3-year old by 5 mL/time, 3-5-year old by 10 mL/time, 5-8-year old by 15 mL/time, 3 times daily. The patients in the treatment group were po administered with Pediatric Compound Four Vitamins and Ferrous Fumarate Powder, < 1 year by 0.5 packet/time, 1-3-year old by 1 packet/time, 4-6-year old by 1.5 packets/time, 7-2-year old by 2 packets/time, one or two times daily. Two weeks were as one course, and two groups were treated for 2 courses. The treatment effects were observed in the two groups after the treatment, and at the same time, the weight, body mass height index (BMI), Hb, Zn, AMS, and Gas levels in serum of children were compared between the two groups before and after the treatment. Results The total effective rates of children in the treatment and control groups were 95.24% and 76.19% with the significant difference (P < 0.05). After the treatment, weight, BMI, Hb, Zn, AMS, Gas levels in the two groups were higher than those before the treatment, and those in the treatment group was significantly higher than the control group, and the differences between the two groups were statistically significant (P < 0.05). Conclusion Pediatric Compound Four Vitamins and Ferrous Powder has good clinical efficacy in the treatment of infantile and children's anorexia, and it can increase body weight and BMI effectively, while improve the symptoms of anemia in children, which is worthy of clinical application.
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