目的 對淄博市中心醫(yī)院中藥注射劑超說明書用藥情況進行調(diào)查分析, 為臨床合理用藥提供參考。方法 隨機抽取2014年淄博市中心醫(yī)院使用中藥注射劑的住院患者病歷200份, 對中藥注射劑的溶媒選擇、用藥劑量或濃度、用藥療程、超適應癥用藥等進行分析評價。結果 中藥注射劑臨床使用廣泛。中藥注射劑存在一定程度溶媒選擇不當、超劑量、超濃度或超療程用藥等超說明書用藥的情況, 超說明書用藥處方占42%。結論 加強處方點評與反饋, 對超說明書用藥進行有效干預, 促進中藥注射劑的合理使用。

Objective To investigate the off-label use of traditional Chinese medicine (TCM) injection in Central Hospital of Zibo, and to provide reference for reasonable application of TCM injection. Methods In-patients (200 cases) using TCM injection in Central Hospital of Zibo in 2014 were randomly extracted, and the selection of solvent, drug dosage or concentration, course of medication, and ultra-indication of TCM injection were analyzed and evaluated. Results TCM injection were widely used in Central Hospital of Zibo. There was a certain degree of off-label use of drugs, including unreasonable choice of solvent, ultra-dosage, ultra-concentration, and ultra-course of medication. The prescription of off-label use of TCM injection accounted for 42%. Conclusion Prescription comments and feedback should be strengthened, and off-label use of TCM injection should be given effective intervention, to promote rational use of TCM injection.

山東省藥學會臨床藥學奧賽康中青年科研資助項目(Sdpa-ask-2013-01)