1片治療帶狀皰疹后遺神經(jīng)痛的臨床療效。方法 選取上海交通大學(xué)醫(yī)學(xué)院附屬第三人民醫(yī)院2013年6月-2015年3月收治的帶狀皰疹后遺神經(jīng)痛患者98例,隨機(jī)分為對照組和治療組,每組各49例。對照組給予布洛芬緩釋膠囊0.3 g/次,2次/d,維生素B1片10 mg/次,3次/d;治療組在對照組的基礎(chǔ)加用元胡止痛片5片/次,3次/d。兩組均連續(xù)治療4周。采用VAS法記錄治療前、治療后24 h、1周、1個(gè)月時(shí)的VAS評分,對兩組患者治療前后的疼痛程度進(jìn)行評估;記錄兩組患者止痛即刻起效時(shí)間、疼痛開始緩解時(shí)間;觀察兩組的臨床療效。結(jié)果 兩組治療后1周、1個(gè)月VAS評分均顯著低于同組治療前(P < 0.05)。治療組在治療后24 h、1周、1個(gè)月VAS評分均顯著低于對照組對應(yīng)的各時(shí)間點(diǎn),其中治療組治療后1周、1個(gè)月VAS評分與對照組比較,差異均具有統(tǒng)計(jì)學(xué)意義(P < 0.05)。治療后,治療組止痛即刻起效時(shí)間短于對照組,但組間比較差異無顯著性,兩組疼痛開始緩解時(shí)間比較差異具有顯著性(P < 0.05),治療組優(yōu)于對照組(P < 0.05)。治療后,對照組和治療組的總有效率分別為89.80%、97.96%,兩組總有效率比較差異有統(tǒng)計(jì)學(xué)意義(P < 0.05)。結(jié)論 元胡止痛片聯(lián)合布洛芬緩釋膠囊和維生素B1片治療帶狀皰疹后遺神經(jīng)痛具有較好的臨床療效,且安全可靠,具有一定的臨床推廣應(yīng)用價(jià)值。;Objective To investigate the clinical effect of Yuanhu Zhitong Tablets combined with Bloven Sustained Release Capsules and Vitamin B1 Tablets in treatment of postherpetic neuralgia. Methods Patients (98 cases) with postherpetic neuralgia in Shanghai 3rd People's Hospital, School of Medicine, Shanghai Jiao Tong University, from June 2013 to March 2015 were randomly divided into control and treatment groups, and each group had 49 cases. The patients in the control group were po administered with Bloven Sustained Release Capsules, 0.3 g/time, twice daily, and Vitamin B1 Tablets, 10 mg/time, three times daily. The patients in the treatment group were po administered with Yuanhu Zhitong Tablets on the basis of control group, 5 tablets/time, three times daily. The patients in two groups were treated for 4 weeks. VAS scores were recorded before treatment, and 24 h, 1 week, and 1 month after the first treatment by VAS method to evaluate the degree of pains. The time for inducing pain remssion and the pain relief time were recorded. After treatment, the efficacy was evaluated. Results After treatment at time point of 1 week and 1 month after the first treatment, VAS scores were significantly reduced in both groups compared than those in the same group before treatment (P < 0.05). VAS scores in the treatment group were significantly lower than those in control group at time point of 24 h, 1 week, and 1 month after the first treatment, and there was difference between two groups t time point of 1 week and 1 month after the first treatment (P < 0.05). There was no significant difference in the time for inducing pain remssion between the two groups after treatment, but the time for pain relief time of treatment group was better than that in the control group, the difference was statistically significant (P < 0.05). After treatment, the efficacies in the control and treatment groups were 89.80% and 97.96%, respectively, and there were significant differences between two groups (P < 0.05). Conclusion Yuanhu Zhitong Tablets combined with Bloven Sustained Release Capsules and Vitamin B1 Tablets has good clinical effect in treatment of in treatment of postherpetic neuralgia with no serious adverse reaction, which has a certain clinical value."/> 1片;帶狀皰疹后遺神經(jīng)痛;療效觀察;Yuanhu Zhitong Tablets;Bloven Sustained Release Capsules;Vitamin B1 Tablets;postherpetic neuralgia"/>

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首頁 > 過刊瀏覽>2015年第30卷第10期 >2015,30(10):1251-1254. DOI:10.7501/j.issn.1674-5515.2015.10.016
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元胡止痛片聯(lián)合布洛芬和維生素B1治療帶狀皰疹后遺神經(jīng)痛的療效觀察

Clinical observation of Yuanhu Zhitong Tablets combined with bloven and vitamin B1 in treatment of postherpetic neuralgia

發(fā)布日期:2015-10-27