目的 比較干預前后江蘇省人民醫(yī)院消化內鏡預防用抗菌藥物的使用情況,為合理使用抗菌藥物提供依據(jù)。方法 采集2013年3-9月、2014年3-9月江蘇省人民醫(yī)院消化內科住院患者應用抗菌藥物的數(shù)據(jù),比較干預前后抗菌藥物的使用強度(AUD)、用藥選擇、給藥時機、用藥療程。結果 干預后,各類手術患者抗菌藥物的AUD都呈下降趨勢。各類抗菌藥物的AUD均有所下降,且第3代頭孢菌素類的AUD顯著降低。第1、2代頭孢菌素類抗菌藥物的使用例數(shù)呈明顯上升趨勢。各類手術術前預防應用抗菌藥物的比例均有所上升。各類手術患者抗菌藥物的用藥療程均有所縮短。結論 通過規(guī)范消化內鏡抗菌藥物預防使用,有效加強了消化內科對抗菌藥物的臨床應用管理,提高了消化內科抗菌藥物使用的合理應用水平。

Objective To compare the prophylactic application of antibiotics in digestive endoscopy in Jiangsu Province Hospital before and after intervention, and to provide valuable reference for rational use of antibiotics. Methods The data of prophylactic application of antibiotics in Department of Gastroenterology in Jiangsu Province Hospital in from March to September 2013, and from March to September 2014 were selected, and the antibacterial use density (AUD), selection of medicine, time of administration, and course of treatment were compared before and after intervention. Results After intervention, the AUD of inpatients with different kinds of operation were declined significantly. The AUD of all kinds of antibiotics were declined, and that of the third generation of cephalosporin was declined significantly. The use of the first and second generation of cephalosporin showed a trend of increasing obviously. Furthermore, the rational rates of preoperative prophylactic application of antibiotics were elevated. The courses of prophylactic application of antibiotics were shortened. Conclusion Through standardizing antibiotic prophylaxis of digestive endoscope, it can not only strengthen the management of clinical application of antibacterial drugs effectively, but also improve the rational use of anti-bacteria in Department of Gastroenterology.