目的 對南京市胸科醫(yī)院肺癌化療輔助用藥的使用情況進(jìn)行分析,為用藥干預(yù)提供依據(jù)。方法 調(diào)取南京市胸科醫(yī)院2014年1月—2015年6月肺癌化療輔助用藥的有關(guān)數(shù)據(jù),并進(jìn)行統(tǒng)計(jì)分析。結(jié)果 肺癌化療輔助用藥中銷售總金額和每例平均金額最高的為中成藥,使用例次最多的為抑酸止吐藥。中成藥中總金額和使用例次最多的均為參芪扶正注射液;止痛類藥物使用金額和使用例次的排序均靠后;抑酸止吐類藥中總金額排序較前的為帕洛諾司瓊注射液和奧美拉唑注射劑,使用例次排序?yàn)榈?和第2位,但每例平均金額較低;每例平均金額最高的為細(xì)胞刺激因子類藥物重組人血小板生成素注射液;保肝類藥物中,使用例次最多的為還原型谷胱甘肽注射劑。結(jié)論 中成藥、抑酸止吐藥以及保肝藥的應(yīng)用均存在一些不合理現(xiàn)象,且癌痛的治療仍然存在不足,因此化療輔助用藥需要加強(qiáng)干預(yù),促進(jìn)合理使用。

Objective To analyze the utilization of lung cancer chemotherapy adjuvant drugs in Nanjing Chest Hospital and to provide a reference for drug intervention. Methods The data of lung cancer chemotherapy adjuvant drugs in Nanjing Chest Hospital from January 2014 to June 2015 were collected and analyzed statistically. Results The total amount and the average cost per case of patients of Chinese patent medicine (CPM) were the most in chemotherapy adjuvant drugs. And use cases for the most was acid suppression and antiemetic drugs. The total amount and use cases of Shenqi Fuzheng Injection ranked the first in CPM. While the total amount and use cases of analgesic drugs both ranked back. The total amount of Palonosetron Hydrochloride Injection and Omeprazole Injection ranked higher in acid suppression and antiemetic drugs, and the use cases were at No.5 and No.2, respectively. While the average cost per case of patients were lower, the average cost per case of patients of Recombinant Human Thrombopoietin Injection was highest in cell stimulating factor drugs. The use cases for the most was Reduced Glutathione for injection in liver-protective drugs. Conclusion There are some irrational phenomena in the use of CPM, acid suppression and antiemetic drugs, and liver-protective drugs, and the treatment of cancer pain is still inadequate according to the data, which needs further efforts to strengthen the intervention, and to promote the rational use.