酮咯酸是一種新一代強效鎮(zhèn)痛的非甾體類抗炎藥。隨著給藥系統(tǒng)和制劑技術(shù)的不斷發(fā)展,酮咯酸除常規(guī)的口服與注射給藥外,還開發(fā)了經(jīng)皮膚、眼部、鼻腔及口腔黏膜的給藥新途徑與新劑型,使酮咯酸具有長效鎮(zhèn)痛和局部給藥局部起效兩大主要特點。酮咯酸新型制劑鎮(zhèn)痛效果良好,且能提高患者的順應(yīng)性和用藥安全性,具有良好的市場前景。

Ketorolac is a new kind of non steroidal agents with potent analgesic activities. New formulation and delivery systems of ketorolac has been developed such as ocular, transdermal, nasal and buccal delivery systems in addition to oral and injection dosage forms, which makes the formulation of ketorolac long-lasting and local effect. The new ketorolac formulations have good analgesic effect, and are objective to improving patient's compliance and security, which have a promising future.

浙江省重點科技創(chuàng)新團隊計劃資助項目(2013TD15)