目的 分析天津市寶坻區(qū)人民醫(yī)院內分泌科住院患者抗菌藥物的使用情況,為抗菌藥物合理使用提供參考。方法 收集2013年1月-2014年12月天津市寶坻區(qū)人民醫(yī)院內分泌科使用抗菌藥物的住院患者374例,對患者的基本情況、感染分布、病原菌分布及其抗菌藥物的使用情況進行分析。結果 374例抗菌藥物使用患者中,女性多于男性,且年齡多集中于61歲以上,患者以2型糖尿病及其相關并發(fā)癥為主,感染部位主要集中在泌尿系和呼吸道,病原菌以革蘭陰性菌為主。單獨使用1種抗菌藥物的比例相對較高,頭孢菌素類使用品種、例次最多,DDDs排序前10位的抗菌藥物中只有左氧氟沙星為口服給藥,其他均為靜脈滴注,頭孢哌酮鈉舒巴坦鈉的DDDs位列第1位。結論 天津市寶坻區(qū)人民醫(yī)院內分泌科住院患者抗菌藥物的臨床應用相對合理。

Objective To analyze the utilization of antibacterial drugs for inpatients in Department of Endocrinology of Tianjin Baodi People's Hospital, and to provide reference for rational application of antibiotics. Methods The inpatients (374 cases) using antibiotics in Department of Endocrinology of Tianjin Baodi People's Hospital from January 2013 to December 2014 were collected. The basic information of patients, distribution of infection, distribution of main pathogenic bacteria, and utilization of antibacterial drugs were analyzed. Results In the inpatients (374 cases) using antibiotics, female were more than male, and the ages of patients were mainly above 61 years old. Most patients were ill with type 2 diabetes and related complications. Infection site were concentrated in urinary tract and respiratory tract. Gram-negative bacteria were the main pathogenic bacteria. Most of patients used one kind of antibiotics. The most variety and case time of using was cephalosporins. Only levofloxacin in top 10 antibiotics in the list of DDDs was orally given, while others were given with iv drip. DDDs of cefoperazone sodium sulbactam sodium was ranked the first. Conclusion The clinical application of antibiotics in Department of Endocrinology of Tianjin Baodi People's Hospital is relatively reasonable.