目的 觀察丹參多酚酸鹽聯(lián)合左旋氨氯地平治療冠心病心絞痛的臨床療效。方法 選取2014年1月-2015年10月長(zhǎng)武縣人民醫(yī)院收治的冠心病心絞痛患者82例，隨機(jī)分為對(duì)照組（40例）和治療組（42例）。對(duì)照組口服苯磺酸左旋氨氯地平片，2.5 mg/次，1次/d。治療組在對(duì)照組基礎(chǔ)上靜脈滴注注射用丹參多酚酸鹽，200 mg加入到5%葡萄糖溶液250 mL中，1次/d。兩組患者均治療2周。觀察兩組的臨床療效，比較兩組患者的臨床癥狀、心電圖改善和血液流變學(xué)指標(biāo)情況。結(jié)果 治療后，對(duì)照組和治療組的總有效率分別為67.50%、88.10%，兩組比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，對(duì)照組和治療組的心電圖改善總有效率分別為67.50%、88.10%，兩組比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組患者的心絞痛發(fā)作次數(shù)和心絞痛持續(xù)時(shí)間均降低，同組治療前后差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；且治療組這些觀察指標(biāo)的下降程度明顯優(yōu)于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組患者的全血黏度、血漿黏度、血小板黏附率均顯著下降，同組治療前后差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；且治療組這些觀察指標(biāo)的下降程度明顯優(yōu)于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 丹參多酚酸鹽聯(lián)合左旋氨氯地平治療冠心病心絞痛具有較好的臨床療效，能緩解臨床癥狀，改善血液流變學(xué)，具有一定的臨床推廣應(yīng)用價(jià)值。

Objective To observe the clinical effect of salvianolate combined with levamlodipine in treatment of angina pectoris of coronary heart disease. Methods Patients (82 cases) with angina pectoris of coronary heart disease in Changwu County People's Hospital from January 2014 to October 2015 were randomly divided into the control group (40 cases) and treatment group (42 cases). Patients in the control group were po administered with Levamlodipine Besylate Tablets, 2.5 mg/time, once daily. Patients in the treatment group were iv administered with Salvianolate for injection on the basis of the control group, 200 mg added to 5% glucose solution 250 mL, once daily. Patients in two groups were treated for 2 weeks. After treatment, the clinical efficacies were evaluated, and clinical symptoms, electrocardiogram improvement, and blood rheology indexes in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 67.50% and 88.10%, respectively, and there was difference between two groups (P<0.05). After treatment, the efficacies of electrocardiogram improvement in the control and treatment groups were 67.50% and 88.10%, respectively, and there was difference between two groups (P<0.05). After treatment, angina attack frequency and angina pectoris duration in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). After treatment, whole blood viscosity, plasma viscosity, and platelet adhesion rate in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). Conclusion Salvianolate combined with levamlodipine has clinical curative effect in treatment of angina pectoris of coronary heart disease, and can relieve clinical symptom, improve blood rheology, which has a certain clinical application value.