目的 觀察參附注射液聯(lián)合胺碘酮治療頻發(fā)室性早搏的臨床療效。方法 選取2012年2月-2015年2月井陘縣醫(yī)院收治的頻發(fā)室性早搏患者140例，隨機(jī)分為對照組和治療組，每組各70例。對照組口服鹽酸胺碘酮片，1片/次，3次/d。治療組在對照組治療基礎(chǔ)上靜脈滴注參附注射液，60 mL/次加入10%葡萄糖注射液500 mL，1次/d。兩組均連續(xù)治療4周。觀察兩組的臨床療效，同時(shí)比較兩組健康和生活質(zhì)量評(píng)分、左室射血分?jǐn)?shù)（LVEF）、心率、氧分壓、6 min步行距離的變化情況。結(jié)果 治療后，對照組和治療組的總有效率分別為81.43%、91.43%，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組生理機(jī)能評(píng)分、生理職能評(píng)分、軀體疼痛評(píng)分、一般健康評(píng)分、精力評(píng)分、社會(huì)功能評(píng)分、情感職能評(píng)分、精神健康評(píng)分、總分均顯著增加，同組治療前后差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；且治療組這些觀察指標(biāo)的改善程度優(yōu)于對照組，兩組比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組患者LVEF、最大心率、氧分壓、6 min步行距離均顯著升高，基礎(chǔ)心率降低，同組治療前后差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；且治療組這些觀察指標(biāo)的改善程度優(yōu)于對照組，兩組比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 參附注射液聯(lián)合胺碘酮治療頻發(fā)室性早搏具有較好的臨床療效，可改善患者的心功能相關(guān)指標(biāo)，提高健康及生存質(zhì)量評(píng)分，具有一定的臨床推廣應(yīng)用價(jià)值。

Objective To observe the clinical curative effect of Shenfu Injection combined with amiodarone in treatment of frequent ventricular premature beat. Methods Patients (140 cases) with frequent ventricular premature beat in Jingxing County Hospital from February 2012 to February 2015 were randomly divided into control and treatment groups, and each group had 70 cases. The patients in the control group were po administered Amiodarone Hydrochloride Tablets, 1 tablet/time, three times daily. The patients in the treatment group were iv administered with Shenfu Injection on the basis of the control group, 60 mL/time added into 10% glucose injection 500 mL, once daily. The patients in two groups were treated for 4 weeks. After treatment, the clinical efficacies were evaluated, and the changes of the scores of health and life quality, LVEF, heart rate, oxygen partial pressure, and 6 min walking distance in two groups before and after treatment were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 81.43% and 91.43%, respectively, and there were differences between two groups (P<0.05). After treatment, physiology score, physiological function score, body pain score, general health score, energy score, social function score, emotional function score, mental health score, and total score in two groups were significantly increased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly higher than those in the control group, with significant difference between two groups (P<0.05). After treatment, LVEF, maximum heart rate, oxygen partial pressure, and 6 min walking distance were significantly increased, and basal heart rates in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups (P<0.05). Conclusion Shenfu Injection combined with amiodarone has clinical curative effect in treatment of frequent ventricular premature beat, and can improve the indicators related cardiac function, also can improve the scores of health and life quality, which has a certain clinical application value.