目的 觀察渴絡(luò)欣膠囊聯(lián)合替米沙坦治療2型糖尿病腎病的臨床療效。方法 選取2015年1月-2015年12月西安市第九醫(yī)院收治的2型糖尿病腎病患者106例，隨機(jī)分為對照組和治療組，每組各53例。對照組口服替米沙坦片，80 mg/次，1次/d。治療組在對照組治療基礎(chǔ)上口服渴絡(luò)欣膠囊，4粒/次，3次/d。兩組均連續(xù)治療8周。觀察兩組的臨床療效，同時(shí)比較兩組治療前后三酰甘油（TG）、膽固醇（TC）、24 h尿蛋白、尿白蛋白排泄率（UAER）。結(jié)果 治療后，對照組和治療組的總有效率分別為81.13%、92.45%，兩組比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組TG、TC、24 h尿蛋白定量、UAER均顯著降低，同組治療前后差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；且治療組這些觀察指標(biāo)的降低程度優(yōu)于對照組，兩組比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 渴絡(luò)欣膠囊聯(lián)合替米沙坦治療2型糖尿病腎病具有較好的臨床療效，可改善生化指標(biāo)，具有一定的臨床推廣應(yīng)用價(jià)值。

Objective To observe the clinical curative effect of Keluoxin Capsules combined with telmisartan in treatment of type 2 diabetic nephropathy. Methods Patients (106 cases) with type 2 diabetic nephropathy in Ninth Hospital of Xi'an from January 2015 to December 2015 were randomly divided into control and treatment groups, and each group had 53 cases. The patients in the control group were po administered with Telmisartan Tablets, 80 mg/time, once daily. The patients in the treatment group were po administered with Keluoxin Capsules on the basis of the control group, 4 grains/time, three times daily. The patients in two groups were treated for 8 weeks. After treatment, the clinical efficacies were evaluated, and the changes of TG, TC, 24 h urine protein, and UAER in two groups before and after treatment were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 81.13% and 92.45%, respectively, and there were differences between two groups (P<0.05). After treatment, TG, TC, 24 h urine protein, and UAER in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). Conclusion Keluoxin Capsules combined with telmisartan has clinical curative effect in treatment of type 2 diabetic nephropathy, and can improve the biochemical indicators, with a certain clinical application value.