目的 回顧分析北京醫(yī)院外科住院病房2010-2015年萬(wàn)古霉素的用藥情況，為臨床合理使用萬(wàn)古霉素提供參考。方法 篩選北京醫(yī)院2010年1月-2015年12月使用萬(wàn)古霉素的外科住院患者的全部病例，提取詳細(xì)病例信息，并對(duì)各科室使用情況、藥敏送檢情況、臨床有效率及用藥合理性進(jìn)行統(tǒng)計(jì)分析。結(jié)果 共篩選出病例454例，其中用藥不合理89例（占19.6%），治療有效的432例，有效率95.2%；萬(wàn)古霉素的總用藥量4 263.3 g，總用藥天數(shù)為3 307 d，限定日劑量（DDD）為2 g/d，藥物利用指數(shù)（DUI）=0.64。結(jié)論 北京醫(yī)院外科病房萬(wàn)古霉素使用基本合理，但仍有部分病例存在使用不規(guī)范情況。

Objective To analyze the usage of vancomycin in the surgical ward of Beijing Hospital during 2010-2015, so as to provide references for the rational use of vancomycin. Methods All hospitalized cases used vancomycin in Beijing Hospital from January 2010 to December 2015 were screened, and the detailed information was extracted. The usage of vancomycin in different departments, drug sensitive test, clinical efficiency percentage, and rationality of usage were then analyzed. Results A total of 454 cases were screened, of which 89 cases (19.6%) were unreasonable and 432 cases (95.2%) showed effective results; The total dosage of 4 263.3 g of vancomycin was used in 3 307 d, the DDD was 2 g/d, therefore, the DUI was 0.64. Conclusion The use of vancomycin in the surgical ward of Beijing Hospital is generally rational, however, some irrational cases are also found.