目的 探討桂枝茯苓丸聯(lián)合克林霉素磷酸酯治療慢性盆腔炎的臨床療效。方法 選取2015年2月-2016年2月在富縣人民醫(yī)院接受治療的慢性盆腔炎患者96例，按照治療方法的差別分成對照組和治療組，每組各48例。對照組口服克林霉素磷酸酯片，0.3 g/次，3次/d。治療組在對照組基礎(chǔ)上口服桂枝茯苓丸，1丸/次，2次/d。兩組患者均治療15 d。觀察兩組的臨床療效，比較兩組炎癥因子和臨床癥狀評分的情況。結(jié)果 治療后，對照組和治療組的總有效率分別為83.33%、95.83%，兩組比較差異有統(tǒng)計學(xué)意義（P<0.05）。治療后，兩組IL-6、MCP-1和hs-CRP均顯著降低，同組治療前后比較差異有統(tǒng)計學(xué)意義（P<0.05）；且治療組這些觀察指標(biāo)的降低程度明顯優(yōu)于對照組，兩組比較差異具有統(tǒng)計學(xué)意義（P<0.05）。治療后，兩組臨床癥狀評分均顯著降低，同組治療前后比較差異有統(tǒng)計學(xué)意義（P<0.05）；且治療組臨床癥狀評分的下降程度明顯優(yōu)于對照組，兩組比較差異具有統(tǒng)計學(xué)意義（P<0.05）。結(jié)論 桂枝茯苓丸聯(lián)合克林霉素磷酸酯治療慢性盆腔炎具有較好的臨床療效，可明顯改善臨床癥狀，降低血清炎性因子水平，具有一定的臨床推廣應(yīng)用價值。

Objective To investigate the clinical effect of Guizhi Fuling Pills combined with clindamycin phosphate in treatment of chronic pelvic inflammatory disease. Methods Patients (96 cases) with chronic pelvic inflammatory disease in Fu County People's Hospital from February 2015 to February 2016 were enrolled in this study. According to the difference treatment plan, patients were divided into control and treatment groups, and each group had 48 cases. Patients in the control group were po administered with Clindamycin Phosphate Tablets, 0.3 g/time, three times daily. Patients in the treatment group were po administered with Guizhi Fuling Pills on the basis of the control group, 1 pill/time, twice daily. Patients in two groups were treated for 15 d. After treatment, the clinical efficacies were evaluated, and inflammatory factors and clinical symptom scores in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 83.33% and 95.83%, respectively, and there was difference between two groups (P<0.05). After treatment, IL-6, MCP-1, and hs-CRP in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). After treatment, the clinical symptom scores in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the clinical symptom score in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). Conclusion Guizhi Fuling Pills combined with clindamycin phosphate has clinical curative effect in treatment of chronic pelvic inflammatory disease, and can significantly improve clinical symptoms, decrease serum inflammatory factors, which has a certain clinical application value.