目的 探討骨康膠囊聯(lián)合碳酸鈣D3片治療老年骨質(zhì)疏松性橈骨遠(yuǎn)端骨折的臨床療效。方法 選擇2012年7月-2015年6月黃石煤炭礦務(wù)局職工醫(yī)院收治的骨質(zhì)疏松性橈骨遠(yuǎn)端骨折患者72例，隨機(jī)分為對(duì)照組和治療組，每組各36例。兩組均給予手術(shù)切開(kāi)復(fù)位處理，對(duì)照組術(shù)后口服碳酸鈣D3片，1.8 g/次，3次/d。治療組在對(duì)照組基礎(chǔ)上口服骨康膠囊，1.2~1.6 g/次，3次/d。兩組患者均治療6個(gè)月。比較兩組的腕關(guān)節(jié)功能恢復(fù)情況、骨代謝、骨密度、住院時(shí)間和骨折愈合時(shí)間。結(jié)果 治療后，對(duì)照組和治療組的優(yōu)良率分別為72.22%、91.67%，兩組比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組TP1NP和BGP均上升，而β-CTX均下降，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；且治療組這些觀察指標(biāo)的改善程度明顯優(yōu)于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組腰椎L2-4、股骨頸、Ward三角和大粗隆骨密度均上升，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；且治療組這些觀察指標(biāo)的上升程度明顯優(yōu)于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，治療組住院時(shí)間和骨折愈合時(shí)間均短于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 骨康膠囊聯(lián)合碳酸鈣D3片可加速老年骨質(zhì)疏松性橈骨遠(yuǎn)端骨折患者術(shù)后骨折愈合速度，縮短住院時(shí)間，促進(jìn)患者骨形成，抑制骨吸收，調(diào)節(jié)骨代謝，提高骨密度，具有一定的臨床推廣應(yīng)用價(jià)值。

Objective To investigate the clinical effect of Gukang Capsules combined with Calcium Carbonate and Vitamin D3 Tablets in treatment of elderly patients with osteoporotic distal radius fractures. Methods Patients (72 cases) with osteoporotic distal radius fractures in Huangshi Mining Hospital from July 2012 to June 2015 were randomly divided into control and treatment groups, and each group had 36 cases. All patients were given open reduction surgery. Patients in the control group were po administered with Calcium Carbonate and Vitamin D3 Tablets, 1.8 g/time, three times daily. Patients in the treatment group were po administered with Gukang Capsules on the basis of the control group, 1.2-1.6 g/time, three times daily. Patients in two groups were treated for 6 months. After treatment, the clinical efficacies were evaluated, and functional recovery of wrist joint, bone metabolism, bone density, hospitalization time, and fracture healing time in two groups were compared. Results After treatment, the excellent rates in the control and treatment groups were 72.22% and 91.67%, respectively, and there was difference between two groups (P<0.05). After treatment, TP1NP and BGP in two groups in two group were significantly increased, but the β-CTX in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups (P<0.05). After treatment, the bone density of lumbar L_2-4, femoral neck, Ward triangle, greater trochanter in two groups were significantly increased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly higher than those in the control group, with significant difference between two groups (P<0.05). After treatment, hospitalization time and fracture healing time in the treatment group were shorter than those in the control group, and there was difference between two groups (P<0.05). Conclusion Gukang Capsules combined with Calcium Carbonate and Vitamin D3 Tablets can accelerate postoperative fracture healing of elderly patients with osteoporotic distal radius fractures, shorten hospitalization time, promote bone formation, inhibit bone resorption, regulate bone metabolism, and increase bone density, which has a certain clinical application value.