目的 分析天津市腫瘤醫(yī)院第二類精神藥品的使用情況和變化趨勢，為促進(jìn)臨床合理用藥提供依據(jù)。方法 對2013-2015年天津市腫瘤醫(yī)院第二類精神藥品的銷售量、銷售金額、用藥頻度（DDDs）、日均藥費(fèi)（DDC）、藥品排序比（B/A）進(jìn)行統(tǒng)計(jì)和分析。結(jié)果 2013-2015年，第二類精神藥品的銷售金額逐年增長，噴他佐辛注射液、地佐辛注射液、咪達(dá)唑侖注射液銷售金額排名始終居前。第二類精神藥物的DDDs逐年增長，地佐辛注射液、噴他佐辛注射液DDDs排名躍居前2位。2013-2014年各種精神藥品的DDC基本相同，噴他佐辛注射液的DDC值較大，躍至首位。2015年所有第二類精神藥品的DDC均低于10元。2015年，各種精神藥品的B/A均接近于1.00。結(jié)論 天津市腫瘤醫(yī)院第二類精神藥品使用基本合理，但個別藥品存在不合理現(xiàn)象。

Objective To investigate the usage and variation tendency of second class psychotropic substances in Tianjin Cancer Hospital, in order to provide reference for rational drug use in clinic. Methods The utilization, consumption sums, frequency of drug use (DDDs), defined daily cost (DDC), and drug sequence ratio (B/A) of second class psychotropic substances in Tianjin Cancer Hospital during 2013 to 2015 were calculated and analyzed. Results The consumption sums of second class psychoactive substances increased rapidly year by year from 2013 to 2015. The consumption sums of Pentazocine Injection, Dezocine Injection, and Midazolam Injection ranked first. DDDs of second class psychoactive substances increased year by year from 2013 to 2015, and DDDs of Dezocine Injection and Pentazocine Injection ranked the first and the second in 2015. In 2013 and 2014, DDC of second class psychotropic substances was basically stable, and DDDs of Pentazocine Injection ranked the first. DDC of all the second class psychotropic substances were lower than 10 Yuan in 2015. B/A of most second class psychotropic substances was closed to 1.00 in 2015. Conclusion The utilization of second class psychotropic substances in Tianjin Cancer Hospital is rational on the whole, but there are still some problems.