目的 探究藤黃健骨片聯(lián)合金烏骨通膠囊治療椎間盤源性腰痛的臨床療效。方法 選取2015年1月—2016年3月在新鄉(xiāng)醫(yī)學(xué)院第一附屬醫(yī)院骨外科接受治療的椎間盤源性腰痛患者122例為研究對象，按照隨機(jī)數(shù)表法將患者分為對照組和治療組，每組各61例。對照組口服金烏骨通膠囊，3粒/次，3次/d。治療組在對照組基礎(chǔ)上口服藤黃健骨片，3~6片/次，2次/d。兩組患者均治療12周。觀察兩組的臨床療效，比較兩組的日本骨科協(xié)會評估治療（JOA）評分和視覺模擬評分法（VAS）評分。結(jié)果 治療后，對照組和治療組的總有效率分別為75.41%、91.80%，兩組比較差異有統(tǒng)計學(xué)意義（P < 0.05）。治療2、4、12周后，兩組JOA評分均顯著升高，同組治療前后比較差異有統(tǒng)計學(xué)意義（P < 0.05）；且治療組JOA評分的升高程度明顯優(yōu)于對照組，兩組比較差異具有統(tǒng)計學(xué)意義（P < 0.05）。治療4、12周后，兩組VAS評分均明顯降低，同組治療前后比較差異有統(tǒng)計學(xué)意義（P < 0.05）；且治療組VAS評分的降低程度明顯優(yōu)于對照組，兩組比較差異具有統(tǒng)計學(xué)意義（P < 0.05）。結(jié)論 藤黃健骨片聯(lián)合金烏骨通膠囊治療椎間盤源性腰痛具有較好的臨床療效，能夠改善臨床癥狀，安全性較好，具有一定的臨床推廣應(yīng)用價值。

Objective To explore the clinical effect of Tenghuang Jiangu Tablets combined with Jinwu Gutong Capsules in treatment of discogenic low back pain. Methods Patients (122 cases) with discogenic low back pain in Department of Bone Surgery of the First Affiliated Hospital of Xinxiang Medical College from January 2015 to March 2016 were randomly divided into control and treatment groups, and each group had 61 cases. Patients in the control group were po administered with Jinwu Gutong Capsules, 3 grains/time, three times daily. Patients in the treatment group were po administered with Tenghuang Jiangu Tablets on the basis of the control group, 3 — 6 tablets/time, twice daily. Patients in two groups were treated for 12 weeks. After treatment, the clinical efficacies were evaluated, and JOA scores and VAS scores in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 75.41% and 91.80%, respectively, and there was difference between two groups (P < 0.05). After treatment for 2, 4, and 12 weeks, the JOA scores in two groups were significantly increased, and the difference was statistically significant in the same group (P < 0.05). And the JOA score in the treatment group was significantly higher than that in the control group, with significant difference between two groups (P < 0.05). After treatment for 4 and 12 weeks, the VAS scores in two groups were significantly decreased, and the difference was statistically significant in the same group (P < 0.05). And the VAS score in the treatment group was significantly lower than that in the control group, with significant difference between two groups (P < 0.05). Conclusion Tenghuang Jiangu Tablets combined with Jinwu Gutong Capsules has clinical curative effect in treatment of discogenic low back pain, can improve clinical symptoms with good safety, which has a certain clinical application value.

河南省醫(yī)學(xué)科技攻關(guān)計劃項(xiàng)目（201403141）