目的 了解貴陽中醫(yī)學(xué)院第一附屬醫(yī)院麻醉藥品的使用情況及變化趨勢，為臨床合理用藥提供依據(jù)。方法 對2013—2015年貴陽中醫(yī)學(xué)院第一附屬醫(yī)院麻醉藥品的用量、銷售金額、用藥頻度（DDDs）、日均藥費(fèi)（DDC）及藥品排序比（B/A）等進(jìn)行統(tǒng)計(jì)和分析。結(jié)果 2013—2015年共收集麻醉藥品處方28 209張，涉及11個(gè)品規(guī)，4種劑型，銷售金額由2013年的42.61萬元上升至2014年的62.48萬元，降至2015年的51.65萬元；麻醉藥品的DDDs排序相對穩(wěn)定，枸櫞酸舒芬太尼注射液的DDDs穩(wěn)居第1位，鹽酸羥考酮緩釋片、注射用瑞芬太尼、鹽酸氯胺酮注射液的DDDs逐年上升，鹽酸嗎啡注射液、芬太尼透皮貼劑的DDDs均有上升趨勢，鹽酸麻黃堿注射液、鹽酸嗎啡緩釋片的DDDs下降明顯。麻醉藥品的DDC均有不同程度的波動，各品種的DDC相差較大。枸櫞酸舒芬太尼注射液、枸櫞酸芬太尼注射液、鹽酸氯胺酮注射液的B/A均為1.00。結(jié)論 貴陽中醫(yī)學(xué)院第一附屬醫(yī)院不斷加強(qiáng)對麻醉藥品的管理，以及藥師的積極干預(yù)，對麻醉藥品的合理應(yīng)用和規(guī)范管理起到了積極有效的作用。

Objective To investigate the application and tendency of narcotic drugs in the First Affiliated Hospital of Guiyang College of Traditional Chinese Medicine, and to provide reference for rational drug use in clinic. Methods The application of narcotic drugs in the First Affiliated Hospital of Guiyang College of Traditional Chinese Medicine from 2013 to 2015 was analyzed retrospectively. The DDDs and the daily drug cost (DDC) and the ratio of the ranked number of the sales amount of drug (B) and the ranked number of DDDs (A) was analyzed. The use frequency of narcotic drugs, the average daily cost of patients with narcotic drugs, whether the amount of drugs use and the number of people using the narcotic drugs synchronized or not were analyzed. Results There were 28 209 prescriptions of narcotic drugs involving 11 varieties and 4 kinds of dosage forms. Consumption sum rosed from 426.1 thousands in 2013 to 624.8 thousands in 2014, and then decreased to 516.5 thousands in 2015. The sequences of DDDs were relatively stable. DDDs of Sufentanil Citrate Injection ranked first. DDDs of Oxycodone Hydrochloride Prolonged-release Tablets, Remifentanil Hydrochloride for injection, and Ketamine Hydrochloride Injection increased year by year. DDDs of Morphine Hydrochloride Injection and Transdermal fentanyl had a rising trend. DDDs of Ephedrine Hydrochloride Injection and Morphine Hydrochloride Sustained-release Tablets declined significantly. DDC of narcotic drugs had different degrees of volatility. And all varieties of DDC differed greatly. B/A of Sufentanil Citrate Injection, Fentanyl Citrate Injection, and Ketamine Hydrochloride Injection were 1.00. Conclusion Strengthening the management of narcotic drugs and the active intervention of pharmacists play a positive and effective role in the rational use and standardized management of narcotic drugs in the First Affiliated Hospital of Guiyang College of Traditional Chinese Medicine.