[關(guān)鍵詞]
[摘要]
目的 分析西安市中心醫(yī)院2014-2016年中藥注射劑的使用情況,為臨床合理用藥提供參考。方法 調(diào)取2014-2016年西安市中心醫(yī)院中藥注射劑的用藥數(shù)據(jù),對品種、銷售金額、用藥頻率(DDDs)、日均費用(DDC)等進行統(tǒng)計、排序和分析;對2014-2016年由中藥注射劑引發(fā)的不良反應(yīng)病例報告進行整理、分析;并利用PASS系統(tǒng)評價中藥注射劑的用藥合理性。結(jié)果 2014-2016年中藥注射劑用藥金額的構(gòu)成比分別為9.35%、9.02%、8.80%;活血化瘀類中藥注射劑的使用金額和DDDs穩(wěn)居前列,其不良反應(yīng)發(fā)生率也較高;抗腫瘤類中藥注射劑的DDC偏高;中藥注射劑引發(fā)的不良反應(yīng)主要表現(xiàn)為皮疹、瘙癢、發(fā)熱、靜脈炎等;中藥注射劑使用中存在無適應(yīng)癥用藥、用法用量不適宜、溶媒不適宜、聯(lián)合用藥不當(dāng)、療程過長等情況。結(jié)論 西安市中心醫(yī)院中藥注射劑使用基本合理,但仍存在不合理用藥情況,臨床藥師應(yīng)加強對不合理用藥的干預(yù),減少不良反應(yīng)的發(fā)生,促進臨床合理用藥。
[Key word]
[Abstract]
Objective To analyze the utilization of traditional Chinese medicine injection in Xi'an Central Hospital from 2014 to 2016, and to provide reference for clinical rational drug use. Methods The drug utilization data of traditional Chinese medicine injections in Xi'an Central Hospital from 2014 to 2016 were collected, and varieties, consumption sum, frequency of drug use (DDDs), and defined daily cost (DDC) were statistically ranked and analyzed. The reports of adverse drug reactions caused by the use of traditional Chinese medicine injections from 2014 to 2016 were collected and analyzed. The PASS clinical pharmacy management system was used to evaluate the rationality of drug use of traditional Chinese medicine injections. Results The constituent ratio of traditional Chinese medicine injections accounted for 9.35%, 9.02% and 8.80% respectively from 2014 to 2016. Consumption sum and DDDs of the Chinese patent injections to promote blood circulation and remove blood stasis were in the forefront, and the incidence of adverse reactions was also higher. DDC of anti-tumor traditional Chinese medicine injection was on the high side. The main adverse reactions caused by traditional Chinese medicine injections were rash, itching, fever, phlebitis, and so on. During the use of Chinese patent injections, problems like inappropriate indications, inappropriate solvent, inappropriate usage and dosage, inappropriate combination of drug use, as well as prolonged therapy, could still be found. Conclusion The utilization of the traditional Chinese medicine injections in Xi'an Central Hospital is basically rational. However, some problems still exist, and it is important for clinical pharmacists to intensify intervention of non-rational drug use in order to decrease the occurrence of ADR, and co-guarantee rational drug use in clinic.
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