目的 探討丹參川芎嗪注射液聯(lián)合注射用尤瑞克林治療急性腦梗死的臨床療效。方法 選取2015年5月-2016年6月在安陽市人民醫(yī)院治療的急性腦梗死患者79例為研究對象，將所有患者采用分層隨機(jī)法分為對照組（39例）和治療組（40例））。對照組緩慢靜脈滴注注射用尤瑞克林，0.15 PNA單位加入到生理鹽水250 mL中，1次/d。治療組在對照組的基礎(chǔ)上靜脈滴注丹參川芎嗪注射液，5 mL加入到生理鹽水250 mL中，1次/d。兩組患者均連續(xù)治療7 d。觀察兩組的臨床療效，比較兩組的NIHSS評分、Barthel評分、血液流變學(xué)指標(biāo)情況。結(jié)果 治療后，對照組和治療組的總有效率分別為71.8%、90.0%，兩組比較差異有統(tǒng)計學(xué)意義（P<0.05）。治療后，兩組NIHSS評分顯著降低，Barthel評分明顯升高，同組治療前后比較差異有統(tǒng)計學(xué)意義（P<0.05）；且治療組這些觀察指標(biāo)的改善程度明顯優(yōu)于對照組，兩組比較差異有統(tǒng)計學(xué)意義（P<0.05）。治療后，兩組全血高切黏度、全血低切黏度、紅細(xì)胞比容、血小板聚集率和纖維蛋白原水平均顯著降低，同組治療前后比較差異有統(tǒng)計學(xué)意義（P<0.05）；且治療組這些觀察指標(biāo)明顯低于對照組，兩組比較差異具有統(tǒng)計學(xué)意義（P<0.05）。結(jié)論 丹參川芎嗪注射液聯(lián)合注射用尤瑞克林治療急性腦梗死具有較好的臨床療效，可促進(jìn)神經(jīng)功能恢復(fù)，提高日常生活能力，改善患者血液流變學(xué)指標(biāo)，具有一定的臨床推廣應(yīng)用價值。

Objective To investigate the effect of Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection combined with Urinary Kallidinogenase for injection in treatment of acute cerebral infarction. Methods Patients (79 cases) with acute cerebral infarction in Anyang People's Hospital from May 2015 to June 2016 were randomly divided into the control group (39 cases) and the treatment group (40 cases). Patients in the control group were slowly iv administered with Urinary Kallidinogenase for injection, 0.15 PNA unit added into normal saline 250 mL, once daily. Patients in the treatment group were iv administered with Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection on the basis of the control group, 5 mL added into normal saline 250 mL, once daily. Patients in two groups were treated for 7 d. After treatment, the clinical efficacies were evaluated, and NIHSS scores, Barthel scores, and blood rheology indexes in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 71.8% and 90.0%, respectively, and there was difference between two groups (P<0.05). After treatment, the NIHSS scores in two groups were significantly decreased, but the Barthel scores in two groups were significantly increased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups (P<0.05). After treatment, the level of high blood viscosity, low blood viscosity, hematocrit, platelet aggregation rate, and fibrinogen in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). Conclusion Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection combined with Urinary Kallidinogenase for injection has clinical curative effect in treatment of acute cerebral infarction, can promote the recovery of nerve function, raise the ability of daily life, and improve the blood rheology index, which has a certain clinical application value.