[關(guān)鍵詞]
[摘要]
目的 探討芪參益氣滴丸聯(lián)合養(yǎng)心氏片治療慢性心力衰竭的臨床療效。方法 選取2015年3月-2016年3月在鳳翔縣醫(yī)院治療的慢性心力衰竭患者100例為研究對象,所有患者隨機分為對照組和治療組,每組各50例。對照組餐后30 min口服養(yǎng)心氏片,3片/次,3次/d。治療組在對照組基礎(chǔ)上口服芪參益氣滴丸,0.5 g/次,3次/d。兩組患者均治療60 d。觀察兩組的臨床療效,比較兩組的心功能指標和6 min步行距離。結(jié)果 治療后,對照組和治療組的總有效率分別為74.0%、92.0%,兩組比較差異有統(tǒng)計學意義(P<0.05)。治療后,兩組左室射血分數(shù)(LVEF)、6 min步行距離均顯著增加,而左室舒張末期內(nèi)徑(LVEDD)、左室收縮末期內(nèi)徑(LVESD)均顯著降低,同組治療前后比較差異有統(tǒng)計學意義(P<0.05);且治療組這些觀察指標的改善程度明顯優(yōu)于對照組,兩組比較差異具有統(tǒng)計學意義(P<0.05)。結(jié)論 芪參益氣滴丸聯(lián)合養(yǎng)心氏片治療慢性心力衰竭具有較好的臨床療效,可改善心功能,提高運動耐量,安全性較好,具有一定的臨床推廣應用價值。
[Key word]
[Abstract]
Objective To explore the clinical effect of Qishen Yiqi Dropping Pills combined with Yangxinshi Tablets in treatment of chronic heart failure. Methods Patients (100 cases) with chronic heart failure in Fengxiang County Hospital from March 2015 to March 2016 were randomly divided into control and treatment groups, and each group had 50 cases. Patients in the control group were po administered with Yangxinshi Tablets 30 min after dinner, 3 tablets/time, three times daily. Patients in the treatment group were po administered with Qishen Yiqi Dropping Pills on the basis of the control group, 0.3 g/time, three times daily. Patients in two groups were treated for 60 d. After treatment, the clinical efficacies were evaluated, and heart function indexes and 6 min walking distance in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 74.0% and 92.0%, respectively, and there was difference between two groups (P<0.05). After treatment, LVEF and 6 min walking distance were significantly increased, but LVEDD and LVESD in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups (P<0.05). Conclusion Qishen Yiqi Dropping Pills combined with Yangxinshi Tablets has clinical curative effect in treatment of chronic heart failure, can improve heart function, and enhance exercise tolerance, with good safety, which has a certain clinical application value.
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