[關(guān)鍵詞]
[摘要]
目的 探討分析荊花胃康膠丸聯(lián)合三聯(lián)療法治療消化性潰瘍的臨床療效。方法 選取2013年10月-2016年10月在天津市中醫(yī)藥研究院附屬醫(yī)院治療的消化性潰瘍患者96例,隨機(jī)分成對(duì)照組和治療組,每組各48例。對(duì)照組患者口服奧美拉唑鎂腸溶片,20 mg/次,2次/d;同時(shí)口服阿莫西林膠囊,1 000 mg/次,2次/d,以及飯后口服克拉霉素片500 mg/次,2次/d。治療組患者在對(duì)照組的基礎(chǔ)上口服荊花胃康膠丸,160 mg/次,3次/d。兩組患者均治療14 d。評(píng)價(jià)治療前后兩組患者胃痛和胃鏡療效以及幽門螺桿菌(Hp)清除率。結(jié)果 治療后,對(duì)照組和治療組胃痛療效分別為81.25%和91.66%,兩組比較差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。對(duì)照組和治療組胃鏡療效分別為85.42%、89.58%,兩組比較差異無統(tǒng)計(jì)學(xué)意義。治療后,對(duì)照組Hp清除率31.25%,顯著低于治療組的83.33%,兩組比較差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論 荊花胃康膠丸治療消化性潰瘍效果確切,與三聯(lián)療法聯(lián)合使用可增強(qiáng)根除Hp作用。
[Key word]
[Abstract]
Objective To investigate the clinical effect of Jinhua Weikang Capsules Combined with triple therapy in treatment of peptic ulcer. Methods Patients (96 cases) with peptic ulcer in Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital from October 2013 to October 2016 were randomly divided into control and treatment groups, and each group had 48 cases. Patients in the control group were po administered with Omeprazole Magnesium Enteric-coated Tablets, 20 mg/time, twice daily, and they were po administered with Amoxicillin Capsules at the same time, 100 mg/time, twice daily, also po administered with Clarithromycin Tablets after meals, 500 mg/time, twice daily. Patients in the treatment group were po administered with Jinhua Weikang Capsules on the basis of the control group, 160 mg/time, three times daily. Patients in two groups were treated for 14 d. After treatment, the stomachache efficacy, gastroscopic figures and Hp clearance rate in two groups before and after treatment were evaluated. Results After treatment, the stomachache efficacy in the control and treatment groups were 81.25% and 91.66%, respectively, and there were differences between two groups (P<0.05). Gastroscopic figures in the control and treatment groups were 85.42% and 89.58%, respectively, and there were no difference between two groups. After treatment, the Hp clearance rate in the control group was 31.25%, which was significantly lower than 83.33% in the treatment group, with significant difference between two groups (P<0.05). Conclusion Jinhua Weikang Capsules has significantly effect in treatment of peptic ulcer, which combined with triple therapy can increase Hp clearance rate.
[中圖分類號(hào)]
[基金項(xiàng)目]