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[摘要]
目的 探討抗菌功能性敷料聯(lián)合糠酸莫米松乳膏治療小兒濕疹的臨床療效。方法 選取北京市海淀醫(yī)院2016年1月-2017年7月接受治療的92例小兒濕疹患者為研究對(duì)象,隨機(jī)分為對(duì)照組和治療組,每組各46例,對(duì)照組患兒涂抹糠酸莫米松乳膏,0.1 mg/次,每晚1次。治療組患兒在對(duì)照組的基礎(chǔ)上外敷抗菌功能性敷料,0.1 mg/次,1~3次/d。兩組患者均連續(xù)治療14 d。治療后,觀察兩組的臨床療效,比較兩組治療前后臨床癥狀、皮損程度評(píng)分和不良反應(yīng)及復(fù)發(fā)情況。結(jié)果 治療后,對(duì)照組和治療組的總有效率分別為84.78%、97.83%,兩組總有效率比較差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。治療后,兩組臨床癥狀和皮損程度評(píng)分均顯著降低,同組治療前后差異有統(tǒng)計(jì)學(xué)意義(P<0.05);治療后治療組臨床癥狀和皮損程度評(píng)分均顯著低于對(duì)照組,兩組比較差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。對(duì)照組和治療組的復(fù)發(fā)率分別為19.57%、4.35%,兩組復(fù)發(fā)率比較差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論 抗菌功能性敷料聯(lián)合糠酸莫米松乳膏治療小兒濕疹療效顯著,可明顯改善患兒臨床癥狀,安全性較高,具有一定的臨床推廣應(yīng)用價(jià)值。
[Key word]
[Abstract]
Objective To investigate the clinical effect of antimicrobial functional dressing combined with Mometasone Furoate Cream in treatment of infantile eczema. Methods Patients (92 cases) with infantile eczema in Beijing Haidian Hospital from January 2016 to July 2017 were randomly divided into control and treatment groups. Each group had 46 cases. Patients in the control group were given Mometasone Furoate Cream, 0.1 mg/time, once every night. Patients in the treatment group were given antimicrobial functional dressing, 0.1 mg/time, 1-3 times/d. All patients were continuously treated for 14 d. After treatment, the clinical efficacy was evaluated, and the clinical symptoms and skin lesions score, adverse reaction, and recurrence in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control and treatment groups were 84.78% and 97.83%, respectively, and there was difference between two groups (P<0.05). After treatment, clinical symptoms and skin lesions score in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). After treatment, clinical symptoms and skin lesions score in the treatment group were lower than those in the control group, and there was difference between two groups (P<0.05). The recurrence rate in the control and treatment groups were 19.57% and 4.35%, respectively, and there was difference between two groups (P<0.05). Conclusion Antimicrobial functional dressing combined with Mometasone Furoate Cream has a significant effect in treatment of infantile eczema, and can significantly improve the clinical symptoms with good safety, which has a certain clinical application value.
[中圖分類號(hào)]
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