隨著藥物基因組學(xué)的飛速發(fā)展，遺傳因素對藥物代謝個體差異的影響越來越受到重視。WHO提出21世紀(jì)，人類的健康問題將逐漸步入預(yù)防醫(yī)學(xué)、預(yù)測醫(yī)學(xué)和個體化醫(yī)療的"3P"時代，而這一理念已成為醫(yī)學(xué)現(xiàn)實(shí)。臨床藥學(xué)是未來醫(yī)院藥學(xué)服務(wù)調(diào)整的重要方向，個體化給藥是臨床藥學(xué)服務(wù)的最終目標(biāo)。綜述了近年來開展最多的與臨床藥物基因檢測有關(guān)的項(xiàng)目，并對當(dāng)前的個體化給藥信息和醫(yī)院藥學(xué)部門開展基因檢測工作的必要性和前瞻性做了深入的探討。

The influence of genetic factorson drug metabolism is becoming more and more important with the rapid development of pharmacogenomics. WHO proposed that human health problems would gradually enter the 3P (preventive, predictable, and personal) medical age in twenty-first century, and this idea has become a medical reality. Clinical pharmacy is the important direction of the future hospital pharmacy service, and individualized drug delivery model will become the ultimate goal of clinical pharmacy service. Recently the projects related to gene detection about drug are reviewed in this article, and personalized medicine information at present and the necessity and prospect of carrying out genetic testing in the Department of Pharmacy are further discussed.