目的 分析2016-2018年河南省洛陽正骨醫(yī)院活血化瘀類中藥注射劑的臨床使用現(xiàn)狀，為臨床合理用藥提供參考。方法 隨機(jī)選取2016-2018年河南省洛陽正骨醫(yī)院骨科手術(shù)患者360例，其中使用丹紅注射液、疏血通注射液、注射用血塞通、紅花注射液、注射用血栓通、燈盞細(xì)辛注射液各60例，對其指征用藥、給藥時(shí)間、聯(lián)合用藥、溶劑選擇、給藥劑量與療程等情況進(jìn)行分析。結(jié)果 無指征用藥79例，占21.94%，其中注射用血塞通和燈盞細(xì)辛注射液的無指征用藥例數(shù)較多，構(gòu)成比分別為35.00%、36.67%。給藥時(shí)間差異較大，術(shù)后24 h以內(nèi)活血化瘀類中藥注射劑的使用例數(shù)最多，構(gòu)成比為48.89%。聯(lián)合用藥81例，占22.5%；注射用血塞通、燈盞細(xì)辛注射液溶劑選擇的錯(cuò)誤率較高，分別為70.00%、66.67%；超劑量給藥7例，占1.94%。結(jié)論 河南省洛陽正骨醫(yī)院活血化瘀類中藥注射劑的使用基本合理，但也存在一定的問題，應(yīng)規(guī)范該類中藥注射劑的臨床應(yīng)用，確保患者安全用藥。

Objective To analyze the clinical use of traditional Chinese medicine (TCM) injections for promoting blood circulation and removing blood stasis in Luoyang Orthopedic-Traumatological Hospital of Henan Province from 2016 to 2018, and to provide reference for clinical rational drug use. Methods A total of 360 patients with orthopedic surgery in Luoyang Orthopedic-Traumatological Hospital of Henan Province from 2016 to 2018 were randomly selected, including Danhong Injection, Honghua Injection, Shuxuetong Injection, Xuesaitong for injection, Xueshutong for injection, and Dengzhanxixin Injection, and each had 60 cases. Indications, time of administration, combination of drugs, choice of solvent, dose and course of treatment, and adverse reactions were analyzed. Results There were 79 cases without indications, accounting for 21.94%. In which, Xuesaitong for injection and Dengzhanxixin Injection had the more cases without indications, accounting for 35.00% and 36.67%. There were significant differences between administration times. The most TCM injections used to promote blood circulation and remove stasis were within 24 h after the operation, accounting for 48.89%. There were 81 cases combined, accounting for 22.5%. Xuesaitong for injection and Dengzhanxixin Injection had the more error rate in solvent selection, accounting for 70.00% and 66.67%. There were 7 cases were over-dosed, accounting for 1.94%. Conclusion The use of traditional Chinese medicine (TCM) injections for promoting blood circulation and removing blood stasis is basically reasonable, but there are also certain problems. The clinical application of traditional Chinese medicine injection should be standardized to ensure the safe use of drugs by patients.

R969.3

河南省中醫(yī)藥科學(xué)研究專項(xiàng)課題（2017ZY2089）；河南省中醫(yī)藥拔尖人才項(xiàng)目（豫中醫(yī)科教[2018]35號）