目的 了解天津市兒童醫(yī)院含β2受體激動劑藥品的使用情況，為臨床藥品管理和合理用藥提供參考。方法 收集天津市兒童醫(yī)院2016-2018年門診藥房使用含β2受體激動劑藥品的相關(guān)數(shù)據(jù)信息，統(tǒng)計藥品相關(guān)指標(biāo)，并分析其變化趨勢。結(jié)果 2016-2018年含β2受體激動劑藥品的用藥金額及使用率呈現(xiàn)逐年遞增趨勢，尤其在2018年，口服用含β2受體激動劑藥品的用藥金額大幅增長，使用率明顯增高。應(yīng)用含β2受體激動劑藥品的用藥頻度（DDDs）排序前3位的藥品依次是鹽酸丙卡特羅片、鹽酸丙卡特羅口服液、布地奈德福莫特羅粉吸入劑（80 μg：4.5 μg）；日均費用（DDC）最高的是硫酸特布他林霧化溶液，口服藥品中DDC最高的是氨溴特羅口服液。結(jié)論 天津市兒童醫(yī)院含β2受體激動劑藥品的用藥金額和使用率與兒童呼吸系統(tǒng)疾病季節(jié)性發(fā)病特點密切相關(guān)，臨床應(yīng)用基本合理，同時應(yīng)及時了解臨床用藥現(xiàn)狀，規(guī)范管理，合理用藥。

Objective To investigate the use of β2 receptor agonist drugs in Tianjin Children's Hospital, and to provide reference for clinical drug management and rational drug use. Methods The data on use of drugs containing β2 receptor agonists in our outpatient pharmacies from 2016 to 2018 and drug-related indicators were collected, and their annual trends were analyzed. Results The amount and use rate of β2 receptor agonist drugs in Tianjin Children's Hospital from 2016 to 2018 showed a trend of increasing year by year, especially in 2018. The amount of oral administration of drugs containing β2 receptor agonists was increased significantly, and the usage rate was increased significantly. The top three drugs for frequency of medication (DDDs) containing β2 receptor agonist drugs were Procaterol Hydrochloride Tablets, Procarterol Hydrochloride Oral Solution, Budesonide Formoterol Powder Inhaler (80 μg:4.5 μg). Average daily cost (DDC) of Terbutaline Sulfate Atomized Solution was the highest. The highest DDC in oral medicine was Ambroxol Oral Solution. Conclusion The dosage and utilization rate of β2 receptor agonist drugs in Tianjin Children's Hospital are closely related to the seasonal incidence characteristics of children's respiratory diseases. The clinical application is basically reasonable. At the same time, the status quo of clinical drug use should be understood, and management should be standardized to promote rational drug use.

R985