目的 探究白芷的最佳水提取工藝。方法 以干浸膏得率、歐前胡素轉(zhuǎn)移率、綜合評(píng)分為評(píng)價(jià)指標(biāo)，采用單因素試驗(yàn)考察浸泡時(shí)間、提取時(shí)間、提取次數(shù)和加水倍數(shù)對(duì)提取效果的影響；根據(jù)單因素試驗(yàn)結(jié)果，采用L₉（3⁴）正交試驗(yàn)法對(duì)浸泡時(shí)間、提取時(shí)間、提取次數(shù)和加水倍數(shù)進(jìn)一步優(yōu)化，并對(duì)優(yōu)化工藝進(jìn)行驗(yàn)證。結(jié)果 優(yōu)化后的提取工藝為加12倍水，提取3次，每次提取0.5 h。優(yōu)化后的工藝所得干浸膏的平均得率為24.25%，歐前胡素平均轉(zhuǎn)移率為17.24%。結(jié)論 優(yōu)化的水提取工藝穩(wěn)定、可行，可用于白芷的水提取。

Objective To explore the best water extraction process of Angelicae Dahuricae Radix. Methods Taking dry extract yield, imperatorin transfer rate and the comprehensive score as evaluation indicators, a single factor test was used to investigate the effects of soaking time, extraction time, extraction times, and water addition multiples on the extraction effect. L₉(3⁴) orthogonal test method was used to further optimize the soaking time, extraction time, extraction times, and water addition ratio, and to verify the optimization process. Results The optimized extraction process was adding 12 times of water, extract 3 times, and each extraction for 0.5 h. The verification test showed that the average yield of the dry extract obtained by the optimized process was 24.25%, and the average transfer rate of imperatorin was 17.24%. Conclusion The optimized water extraction process is stable and feasible. It can be used for the water extraction of Angelicae Dahuricae Radix.

R977

安徽省科技重大專項(xiàng)（17030801009）