目的 探討仙鹿口服液聯(lián)合西地那非治療勃起功能障礙的臨床療效。方法 選取2019年8月—2020年9月河南省中醫(yī)院接診的120例男性勃起功能障礙患者，隨機分為對照組和治療組，每組各60例。對照組在性生活0.5～4 h前口服枸櫞酸西地那非片，50 mg/次，1次/d；治療組在對照組治療基礎上口服仙鹿口服液，10 mL/次，3次/d。兩組3個月為1個療程，或遵醫(yī)囑。觀察兩組的臨床療效，比較兩組治療前后國際勃起功能指數(shù)-5（IIEF5）評分、睪酮（T）、雌二醇（E₂）的變化情況。結果 治療后，治療組總有效率為83.3%，較對照組60.0%更高（P<0.05）。治療后，兩組IIEF-5評分、T水平均顯著升高，而E₂激素水平均較治療前有所降低（P<0.05）；治療后，治療組IIEF-5評分、T水平高于對照組，而E₂激素水平低于對照組（P<0.05）。結論 仙鹿口服液聯(lián)合西地那非治療男性勃起功能障礙具有較好的臨床療效，能顯著改善患者勃起功能，值得在臨床上應用推廣。

Objective To investigate the effects of Xianlu Oral Liquid combined with sildenafil in treatment of male erectile dysfunction.Methods A total of 120 male patients with erectile dysfunction admitted to Henan Hospital of Traditional Chinese Medicine from August 2019 to September 2020 were selected and randomly divided into control group and treatment group, with 60 patients in each group. Patients in the control group were po administered with Sildenafil Citrate Tablets before sexual life, 50 mg/time, once daily. Patients in the treatment group were po administered with Xianlu Oral Liquid on the basis of the control group, 10 mL/time, three times daily. One course of treatment lasted 3 months for both groups, or as prescribed by the doctor. The clinical efficacy of the two groups was observed, and the changes of international erectile function index -5 (IIEF5) score, testosterone (T) and estradiol (E₂) before and after treatment were compared between the two groups.Results After treatment, the total clinical effective rate of the study group was 83.3%, and significantly higher than that of the control group (P<0.05). After treatment, IIEF-5 score and T level were significantly increased in both groups, but E₂ hormone level was decreased compared with before treatment (P<0.05). After treatment, the level of IIEF-5 and T in the treatment group was higher than that in the control group, but the level of E₂ hormone in the treatment group was lower than that in the control group (P<0.05).Conclusion Xianlu Oral Liquid combined with sildenafil has a good clinical effect in the treatment of male erectile dysfunction, and can significantly improve the erectile function of patients, which is worthy of clinical application and promotion.

R98