目的 分析江蘇省南京地區(qū)2017—2019年53家醫(yī)院抗流感藥物的臨床應用情況與變化趨勢，為其臨床合理使用提供參考依據(jù)。方法 采用用藥頻度（DDDs）排序法與金額排序法，對南京地區(qū)53家醫(yī)院2017—2019年使用的抗流感藥物的品種、銷售金額、構(gòu)成比、用藥頻度（DDDs）、限定日費用（DDC）等進行回顧性統(tǒng)計和分析。結(jié)果 2017—2019年，南京地區(qū)抗流感藥物的年銷售金額與年DDDs逐年增長；炎琥寧與奧司他韋2種藥物的銷售金額連續(xù)3年位列前茅，且所占總銷售金額的比例3年均超過50%。金剛烷胺、炎琥寧、板藍根與奧司他韋4種藥物的DDDs值連續(xù)3年位于前4位，且所占總DDDs的比例3年均超過80%，金剛乙胺持續(xù)排在末尾。結(jié)論 抗流感藥物在南京地區(qū)醫(yī)院應用廣泛，銷售金額與使用量均呈快速增長的趨勢，部分藥物的DDC呈降低趨勢。

Objective To analyze the application of anti-influenza virus drugs in 53 hospitals in Nanjing area from 2017 to 2019 and provide a reference for its clinical.Methods Using the medication frequency (DDDs) and the sum of money of consumption (DDC), to analysis the varieties, sales amount, composition ratio, medication frequency and daily drug cost of anti-influenza virus drugs in 53 hospitals in Nanjing area in the study of retrospective statistics.Results The total amount and DDDs of use of anti-influenza virus drugs had increased year by year. The three-year sales of Oseltamivir and Yanhuning were ranked in the top three, and the proportion were more than 50%. The three-year DDDs of Oseltamivir, Amantadine, Yanhuning and Banlangen were ranked in the top four, and the proportion were more than 80%. Rimantadine continue to be at the end.Conclusion The anti-influenza virus drugs are widely used in hospitals in Nanjing, the sales amount and usage as a whole showed a trend of stabilization after growth. The DDC of the some drugs is decresing.

R978.7

江蘇省政策引導類計劃項目（BR2020043）；南京大學醫(yī)院管理研究所管理項目課題（NDYG2019006）