目的 探討橘紅痰咳液聯(lián)合復(fù)方甲氧那明治療感染后咳嗽的臨床效果。方法 選擇2018年1月-2020年12月天津中醫(yī)藥大學(xué)第一附屬醫(yī)院急診科收治的140例感染后咳嗽患者為研究對(duì)象，根據(jù)用藥差別分為對(duì)照組（67例）和治療組（73例），對(duì)照組口服復(fù)方甲氧那明膠囊，2粒/次，3次/d。治療組在對(duì)照組的基礎(chǔ)上口服橘紅痰咳液，20 mL/次，3次/d。兩組療程最長(zhǎng)為7 d。觀察兩組患者臨床療效，比較治療前后兩組患者視覺模擬咳嗽癥狀積分（VAS評(píng)分）、萊切斯特咳嗽問(wèn)卷中文版（LCQ-MC）評(píng)分和止咳時(shí)間。結(jié)果 經(jīng)治療，對(duì)照組愈顯率為65.67%，顯著低于治療組的82.19%（P<0.05）。治療后，兩組VAS評(píng)分明顯降低，而LCQ-MC各維度評(píng)分明顯升高（P<0.05），且治療組患者VAS和LCQ-MC評(píng)分顯著好于對(duì)照組（P<0.05）。治療后，治療組咳嗽緩解時(shí)間及咳嗽停止時(shí)間均顯著短于對(duì)照組（P<0.05）。結(jié)論 橘紅痰咳液聯(lián)合復(fù)方甲氧那明治療感染后咳嗽效果良好，可進(jìn)一步改善臨床癥狀，縮短咳嗽病程，具有一定臨床推廣應(yīng)用價(jià)值。

Objective To investigate the clinical effect of Juhong Tanke Liquid combined with compound methoxyphenamine in treatment of post-infectious cough. Methods Patients (140 cases) with post-infectious cough in the First Teaching Hospital of Tianjin University of Traditional Chinese Medicine from January 2018 to December 2020 were divided into control (67 cases) and treatment (73 cases) groups based on different treatments. Patients in the control group were po administered with Compound Methoxyphenamine Hydrochloride Capsules, 2 grains/time, three times daily. Patients in the treatment group were po administered with Juhong Tanke Liquid, 20 mL/time, three times daily. Patients in two groups were treated for 7 d. After treatment, the clinical efficacy was evaluated, the improvement time of clinical symptoms, the scores of VAS and LCQ-MC, and cough relief time in two groups before and after treatment were compared. Results After treatment, the cured and markedly effective rate in the control group was 65.67%, which was significantly lower than 82.19% in the treatment group (P<0.05). After treatment, the scores of VAS in two groups were significantly decreased, while the scores of LCQ-MC were significantly increased (P<0.05), and the scores of VAS and LCQ-MC in the treatment group were significantly better than those in the control group (P<0.05). After treatment, the cough relief time and cough stop time in the treatment group were significantly less than those in the control group (P<0.05). Conclusion The effect of Juhong Tanke Liquid combined with compound methoxyphenamine in treatment of post-infectious cough is good, can further improve the clinical symptoms and shorten the course of cough, which has a certain clinical application value.

R974

天津中醫(yī)藥大學(xué)第一附屬醫(yī)院“拓新工程”科研課題（201909）