[關(guān)鍵詞]
[摘要]
目的 探討丹紅注射液治療冠心病心絞痛的療效觀察。方法 選取2016年6月—2018年5月鄭州市金水區(qū)總醫(yī)院收治的80例冠心病心絞痛患者,隨機分為對照組和治療組,每組各40例。對照組口服阿司匹林腸溶片100 mg,硫酸氫氯吡格雷片75 mg,阿托伐他汀鈣片40 mg,均為1次/d。治療組在對照組的基礎(chǔ)上靜脈滴注丹紅注射液,100 mL加入生理鹽水40 mL,1次/d。兩組治療4周。觀察兩組患者心電圖療效,比較治療前后兩組患者臨床癥狀積分、血液流變學(xué)指標(biāo)、心功能分級和不良反應(yīng)。結(jié)果 治療后,治療組總有效率為95.0%,明顯高于對照組的75.0%(P<0.05)。治療后,兩組臨床癥狀積分均顯著降低(P<0.05),且治療組臨床癥狀積分明顯低于對照組(P<0.05)。治療后,兩組患者血液流變學(xué)指標(biāo)和心功能分級均較治療前顯著改善(P<0.05);且治療組改善效果優(yōu)于對照組(P<0.05)。治療組患者不良反應(yīng)發(fā)生率明顯低于對照組(P<0.05)。結(jié)論 常規(guī)療法聯(lián)合丹紅注射液治療冠心病心絞痛可達到更好的療效。
[Key word]
[Abstract]
Objective To investigate the curative effect of Danhong Injection in treatment of angina pectoris of coronary heart disease. Methods Patients (80 cases) with angina pectoris of coronary heart disease in Zhengzhou Jinshui General Hospital from June 2016 to May 2018 were randomly divided into control and treatment groups, and each group had 40 cases. Patients in the control group were po administered with Aspirin Enteric-coated Tablets 100 mg, Clopidogrel Hydrogen Sulphate Tablets 75 mg, and Atorvastatin Calcium Tablets 40 mg, once daily. Patients in the treatment group were iv administered with Danhong Injection on the basis of the control group, 100 mL added into normal saline 40 mL, once daily. Patients in two groups were treated for 4 weeks. After treatment, the ECG evaluation was evaluated, the clinical symptom scores, hemorheological indexes, cardiac function grading, and adverse reactions in two groups before and after treatment were compared. Results After treatment, the clinical effective rate of the treatment group was 95.0%, which was significantly higher than 75.0% of the control group (P < 0.05). After treatment, clinical symptom scores in both groups were significantly decreased (P < 0.05), and the clinical symptom score of the treatment group was significantly lower than that of the control group (P < 0.05). After treatment, hemorheology indexes and cardiac function grading in two groups were significantly improved compared with before treatment (P < 0.05). After treatment, the improvement of hemorheology and cardiac function in the treatment group was better than that in the control group (P < 0.05). The incidence of adverse reactions in the treatment group was significantly lower than that in the control group (P < 0.05). Conclusion The routine therapy combined with Danhong Injection can achieve better effect in the treatment of angina pectoris of coronary heart disease.
[中圖分類號]
R972
[基金項目]